How to travel from Prague to Brussels

Thu, Apr 02
+ Add return
Travel by train, bus, flight with
FlixBus
Ryanair
Deutsche Bahn
Brussels Airlines
Smartwings
1,000+ more
FlixBus
Ryanair
Deutsche Bahn
Brussels Airlines
Smartwings
1,000+ more
QR-Code
Scan to get our free app
Use our app to get live travel updates and book mobile tickets for trains, buses, flights, and ferries.
App Store
rate4.9
42K ratings
Google Play
rate4.6
136K reviews

Travel Information

Compare train, bus, and flight for Prague to Brussels

Omio recommends booking the flight as it is the most popular option from Prague to Brussels among Omio's users. If you are prioritising price take the bus with prices starting from $49. For those with little time consider booking a flight which can get you there in 3h 21m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.6kg. The ticket price range depends on the travel mode: a bus costs an average of $49, and a flight costs an average of $26.

Distance: 445 miles (717 km)

Compare flight with

Most popular
Flight
Train
Bus

$133

Average price

$121

Average price

$83

Average price

Cheapest

6h 21m

Average total duration

Fastest

3h 21m

Onboard

+

3h 0m

Additional time*

12h 17m

Average total duration

11h 47m

Onboard

+

30m

Additional time*

15h 10m

Average total duration

14h 40m

Onboard

+

30m

Additional time*

2.2 - 4.3kg

CO2 emissions

0.2 - 0.6kg

CO2 emissions

Lowest

0.7 - 1.8kg

CO2 emissions

Ryanair

Most popular airline

Deutsche Bahn

Most popular train company

FlixBus

Most popular bus company

Direct Options

Direct Options

Direct Options

Additional time: Average total travel duration to departure point, security checks and transfers.

Travel options
from Prague to Brussels

How to get from Prague to Brussels by train, bus or flight.

Our recommendation

train

The best way to travel from Prague to Brussels is by taking a train because it’s the best combination of price and speed.

  • České dráhyrj 178 · ICE 548 · ICE 12
    08:31AM11h04
    Prague hlavní nádraží
    07:35PMBrussels-Midi
    $1421One-way
    2 transfers

Cheapest

  • České dráhyrj 178 · ICE 548 · ICE 12
    08:31AM11h04
    Prague hlavní nádraží
    07:35PMBrussels-Midi
    $1421One-way
    2 transfers

Fastest

  • RyanairFR 69
    02:35PM1h30
    Prague Vaclav Havel Airport
    04:05PMBrussels South Charleroi Airport
    $1951One-way
    0 transfers

Other options

  • Alibus452
    06:05PM15h22
    Prague hlavní nádraží
    09:27AMBrussels-Midi
    $2241One-way
    0 transfers
  • Deutsche BahnEX 356 · 3574 · ICE 528 · ICE 318
    11:35AM12h00
    Prague hlavní nádraží
    11:35PMBrussels-Midi
    $3051One-way
    3 transfers
  • Deutsche BahnRJ 382 · ICE 2506 · ICE 318
    10:31AM13h04
    Prague hlavní nádraží
    11:35PMBrussels-Midi
    $3191One-way
    2 transfers
  • FlixBusFlixBus
    04:15PM15h05
    Praha, ÚAN Florenc
    07:20AMBrussels, Brussels South (Gare du Midi)
    $1711One-way
    0 transfers
  • FlixBusFlixBus
    11:05PM14h50
    Praha, ÚAN Florenc
    01:55PMBrussels, Brussels South (Gare du Midi)
    $1771One-way
    0 transfers
  • FlixBusFlixBus · FlixBus
    09:50PM16h05
    Praha, Na Knížecí
    01:55PMBrussels, Brussels South (Gare du Midi)
    $1961One-way
    1 transfer
  • SmartwingsQS1002
    05:15PM1h30
    Prague Vaclav Havel Airport
    06:45PMBrussels Airport
    $2091One-way
    0 transfers
  • Brussels AirlinesSN2812
    06:45PM1h30
    Prague Vaclav Havel Airport
    08:15PMBrussels Airport
    $2371One-way
    0 transfers
  • Brussels AirlinesSN2814
    09:15PM1h30
    Prague Vaclav Havel Airport
    10:45PMBrussels Airport
    $2371One-way
    0 transfers

Find all the dates and times for this journey by train, bus, flight, and ferry .

Compare prices and tickets Prices for trains, buses and flights

Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Wed
Apr 01
Thu
Apr 02
Fri
Apr 03
Sat
Apr 04
Sun
Apr 05
Mon
Apr 06
Tue
Apr 07
Wed
Apr 08
Thu
Apr 09
Fri
Apr 10
Sat
Apr 11
Sun
Apr 12
Mon
Apr 13
Tue
Apr 14
Wed
Apr 15
Thu
Apr 16
Fri
Apr 17
Sat
Apr 18
Sun
Apr 19
Mon
Apr 20
Tue
Apr 21

How to get from Prague to Brussels

The Best Way According to our Users

When it comes to choosing a method of transportation from Prague to Brussels, 70,86% of our customers do not hesitate to choose the flight as their preferred way to travel. Nowadays, passengers who want to fly around Europe have more options than ever before. With dozens of budget airlines covering several routes which connect to virtually all European countries, taking a flight to reach your desired destination is easy and inexpensive. The low fares and the short flight time are, among others, some of the reasons why our users choose the airplane as the best way to get from Prague to Brussels, even if they have to face baggage limitations and long lines at check-in and security control. You can book your flights with Omio to make sure you are always taking the fastest route or getting the best deal. You can also add extra luggage and book securely with several methods of payment such as Apple Pay, PayPal and more.

Search on Omio to find cheap tickets from Prague to Brussels. It’s easy to find the most attractive prices and choose your preferred route for your journey. Book on web or app, and travel with your mobile ticket —without the stress of printing your ticket.

More than 1,000 travel companies trust us to sell their tickets all in one place.

Trenitalia
Easyjet
Deutsche Bahn
SNCF

FAQs: Travel from Prague to Brussels

Travel to Brussels easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Prague to Brussels.

FAQs
There are 3 options to travel between Prague and Brussels including taking a train, bus, and flight.
The cheapest way to travel from Prague to Brussels is a train with an average price of $16 (€13).

This is compared to other travel options from Prague to Brussels:

A train is $10 (€8) less than a flight for this route with tickets for a flight from Prague to Brussels costing on average $26 (€21).

A train is $33 (€27) less than a bus for this route with tickets for a bus from Prague to Brussels costing on average $49 (€40).

The fastest way to travel from Prague to Brussels is by flight with an average journey time of 1h 30m.

Other travel options to Brussels take longer:

Train takes on average 10h 55m.

Bus takes on average 12h 0m.

The distance from Prague to Brussels is approximately 445 miles (717 km).
The average frequency per day from Prague to Brussels is:
  • Around 38 flights per day.
  • Around 18 buses per day.
  • Around 7 trains per day.

However, we recommend checking specific travel dates for your route between Prague and Brussels as scheduled services by train, bus, and flight can vary by season or day of the week.

These are the most popular departure and arrival points from Prague to Brussels:
  • Flights mostly depart from Prague Vaclav Havel Airport and arrive in Brussels Airport.
  • Trains mostly depart from Prague hlavní nádraží and arrive in Brussels-Midi.
  • Buses mostly depart from Praha, ÚAN Florenc and arrive in Brussels, Brussels South (Gare du Midi).
If finding a good deal is your main consideration for your trip from Prague to Brussels, then we'll help you find the best value travel companies for you:
  • Travel with FlixBus, BlaBlaCar Bus to go to Brussels by bus.
  • Travel with Deutsche Bahn, České dráhy, Alibus, European Sleeper to go to Brussels by train.
  • Travel with Ryanair, Brussels Airlines, Smartwings, Buzz, KLM, KLM Cityhopper, LOT Polish Airlines, Lufthansa, Cityjet, Sas Airways, Helvetic Airways, Swiss, Air Baltic, Lufthansa Cityline, TAP Portugal to go to Brussels by flight.
Yes, there are direct services available from Prague to Brussels with the following travel companies:
  • 2 direct buses per day with FlixBus.
  • 0 direct trains per day with European Sleeper.
  • 4 direct flights per day with Ryanair, Brussels Airlines, Buzz.
Omio customers who travel from Prague to Brussels often also extend their vacation to go to Paris, Amsterdam, Bruges, London, Luxembourg. Omio can help you plan your trip by finding the best connections between Brussels and these popular destinations at a great price.
HomeTravelTravel to BelgiumTravel to BrusselsHow to travel from Prague to Brussels

The Omio App Makes Travel Planning Easy

We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.

ios-badge
android-badge
Hand With Phone