How to travel from Prague to Brussels

Fri, Jun 26
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Travel by train, bus, flight with
Ryanair
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Deutsche Bahn
Brussels Airlines
Buzz
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Ryanair
FlixBus
Deutsche Bahn
Brussels Airlines
Buzz
1,000+ more
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Travel Information

Compare train, bus, and flight for Prague to Brussels

Omio recommends booking the flight as it is the most popular option from Prague to Brussels among Omio's users. If you are prioritising price take the bus with prices starting from $48. For those with little time consider booking a flight which can get you there in 3h 21m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.6kg. The ticket price range depends on the travel mode: a bus costs an average of $48, and a flight costs an average of $26.

Distance: 445 miles (717 km)

Compare flight with

Most popular
Flight
Train
Bus
Driving

$153

Average price

$122

Average price

$83

Average price

Cheapest

$181

Average price

(fuel + tolls)

6h 21m

Average total duration

Fastest

3h 21m

Onboard

+

3h 0m

Additional time*

12h 20m

Average total duration

11h 50m

Onboard

+

30m

Additional time*

15h 24m

Average total duration

14h 54m

Onboard

+

30m

Additional time*

8h 49m

Average total duration

(door-to-door)

2.2 - 4.3kg

CO2 emissions

0.2 - 0.6kg

CO2 emissions

Lowest

0.7 - 1.8kg

CO2 emissions

-

CO2 emissions

Ryanair

Most popular airline

Deutsche Bahn

Most popular train company

FlixBus

Most popular bus company

Your own car or car rental

Direct Options

Direct Options

Direct Options

Direct Options

Additional time: Average total travel duration to departure point, security checks and transfers.

The cheapest way to travel from Prague to Brussels is a bus with an average price of $83 (€69).

This is compared to other travel options from Prague to Brussels:

A bus is $39 (€32) less than a train for this route with tickets for a train from Prague to Brussels costing on average $122 (€101).

A bus is $70 (€58) less than a flight for this route with tickets for a flight from Prague to Brussels costing on average $153 (€127).

The fastest way to travel from Prague to Brussels is by flight with an average journey time of 3h 21m.

Other travel options to Brussels take longer:

Train takes on average 11h 50m.

Bus takes on average 14h 54m.

It's helpful to compare your options as there are 3 ways to travel between Prague and Brussels including taking a train, bus, and flight.
We recommend using the flight as it is the most popular way to get from Prague to Brussels among Omio's users.

Travel options
from Prague to Brussels

How to get from Prague to Brussels by train, bus or flight.

Our recommendation

bus

The best way to travel from Prague to Brussels is by taking a bus because it’s the best combination of price and speed.

  • RegioJet a.s.(Prague -> London)
    6:00 PM12h00
    Praha, ÚAN Florenc
    6:00 AMBrussels, Brussels South (Gare du Midi)
    $721One-way
    0 transfers

Cheapest

  • RegioJet a.s.(Prague -> London)
    6:00 PM12h00
    Praha, ÚAN Florenc
    6:00 AMBrussels, Brussels South (Gare du Midi)
    $721One-way
    0 transfers

Fastest

  • Brussels AirlinesSN2810
    11:50 AM1h30
    Prague Vaclav Havel Airport
    1:20 PMBrussels Airport
    $3211One-way
    0 transfers

Other options

  • České dráhyrj 382 · ICE 546 · ICE 10
    10:31 AM11h04
    Prague hlavní nádraží
    9:35 PMBrussels-Midi
    $1141One-way
    2 transfers
  • České dráhyrj 178 · ICE 548 · ICE 12
    8:31 AM11h04
    Prague hlavní nádraží
    7:35 PMBrussels-Midi
    $1141One-way
    2 transfers
  • České dráhyrj 384 · ICE 640 · ICE 14
    6:31 AM11h04
    Prague hlavní nádraží
    5:35 PMBrussels-Midi
    $1141One-way
    2 transfers
  • FlixBusFlixBus
    11:05 PM14h50
    Praha, ÚAN Florenc
    1:55 PMBrussels, Brussels South (Gare du Midi)
    $821One-way
    0 transfers
  • FlixBusFlixBus · FlixBus · FlixBus
    8:25 PM17h30
    Praha, Zličín
    1:55 PMBrussels, Brussels South (Gare du Midi)
    $871One-way
    2 transfers
  • FlixBusFlixBus · FlixBus
    11:05 AM14h40
    Praha, ÚAN Florenc
    1:45 AMBrussels, Brussels South (Gare du Midi)
    $881One-way
    1 transfer
  • Lot Polish AirlinesLO522 · LO231
    6:05 PM4h30
    Prague Vaclav Havel Airport
    10:35 PMBrussels Airport
    $2571One-way
    1 transfer
  • Lot Polish AirlinesLO528 · LO233
    12:45 PM5h55
    Prague Vaclav Havel Airport
    6:40 PMBrussels Airport
    $2571One-way
    1 transfer
  • Lot Polish AirlinesLO524 · LO237
    9:55 AM6h05
    Prague Vaclav Havel Airport
    4:00 PMBrussels Airport
    $2571One-way
    1 transfer

Find all the dates and times for this journey by train, bus, flight, and ferry .

Compare prices and tickets Prices for trains, buses and flights

Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

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How to get from Prague to Brussels

The Best Way According to our Users

When it comes to choosing a method of transportation from Prague to Brussels, 70,86% of our customers do not hesitate to choose the flight as their preferred way to travel. Nowadays, passengers who want to fly around Europe have more options than ever before. With dozens of budget airlines covering several routes which connect to virtually all European countries, taking a flight to reach your desired destination is easy and inexpensive. The low fares and the short flight time are, among others, some of the reasons why our users choose the airplane as the best way to get from Prague to Brussels, even if they have to face baggage limitations and long lines at check-in and security control. You can book your flights with Omio to make sure you are always taking the fastest route or getting the best deal. You can also add extra luggage and book securely with several methods of payment such as Apple Pay, PayPal and more.

Search on Omio to find cheap tickets from Prague to Brussels. It’s easy to find the most attractive prices and choose your preferred route for your journey. Book on web or app, and travel with your mobile ticket —without the stress of printing your ticket.

More than 1,000 travel companies trust us to sell their tickets all in one place.

Trenitalia
Easyjet
Deutsche Bahn
SNCF

FAQs: Travel from Prague to Brussels

Travel to Brussels easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Prague to Brussels.

FAQs
There are 3 options to travel between Prague and Brussels including taking a train, bus, and flight.
The cheapest way to travel from Prague to Brussels is a bus with an average price of $83 (€69).

This is compared to other travel options from Prague to Brussels:

A bus is $39 (€32) less than a train for this route with tickets for a train from Prague to Brussels costing on average $122 (€101).

A bus is $70 (€58) less than a flight for this route with tickets for a flight from Prague to Brussels costing on average $153 (€127).

The fastest way to travel from Prague to Brussels is by flight with an average journey time of 3h 21m.

Other travel options to Brussels take longer:

Train takes on average 11h 50m.

Bus takes on average 14h 54m.

The distance from Prague to Brussels is approximately 445 miles (717 km).
The average frequency per day from Prague to Brussels is:
  • Around 39 flights per day.
  • Around 15 buses per day.
  • Around 7 trains per day.

However, we recommend checking specific travel dates for your route between Prague and Brussels as scheduled services by train, bus, and flight can vary by season or day of the week.

These are the most popular departure and arrival points from Prague to Brussels:
  • Flights mostly depart from Prague Vaclav Havel Airport and arrive in Brussels Airport.
  • Trains mostly depart from Prague hlavní nádraží and arrive in Brussels-Midi.
  • Buses mostly depart from Praha, ÚAN Florenc and arrive in Brussels, Brussels South (Gare du Midi).
If finding a good deal is your main consideration for your trip from Prague to Brussels, then we'll help you find the best value travel companies for you:
  • Travel with Ryanair, Brussels Airlines, Buzz, Smartwings, KLM, Lot Polish Airlines, KLM Cityhopper, Cityjet, Lufthansa, Sas Airways, Helvetic Airways, Swiss, Air Baltic, Lufthansa Cityline, TAP Portugal to go to Brussels by flight.
  • Travel with FlixBus, BlaBlaCar Bus to go to Brussels by bus.
  • Travel with Deutsche Bahn, České dráhy, Alibus, ÖBB | Euro City (EC), České dráhy (ČD), ÖBB | Railjet to go to Brussels by train.
Yes, there are direct services available from Prague to Brussels with the following travel companies:
  • 4 direct flights per day with Ryanair, Brussels Airlines, Buzz, Smartwings.
  • 2 direct buses per day with FlixBus.
  • 0 direct trains per day with Alibus.
Omio customers who travel from Prague to Brussels often also extend their vacation to go to Paris, Amsterdam, Bruges, London, Luxembourg. Omio can help you plan your trip by finding the best connections between Brussels and these popular destinations at a great price.
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