Des Moines, IA to Jacksonville, FL bus

Sat, Apr 04
+ Add return
FlixBus
Alsa
BlaBlaCar Bus
Costa Verde
Rede Expressos
2,000+ travel companies
FlixBus
Alsa
BlaBlaCar Bus
Costa Verde
Rede Expressos
2,000+ travel companies
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Travel Information

Compare bus and flight for Des Moines, IA to Jacksonville, FL

Omio recommends booking the flight as it is the most popular option from Des Moines, IA to Jacksonville, FL among Omio's users. If you are prioritising price take the bus with prices starting from $283. For those with little time consider booking a flight which can get you there in 5h 55m. The ticket price range depends on the travel mode: a bus costs an average of $283, and a flight costs an average of $458.

Distance: 1024 miles (1648 km)

Compare bus with

Bus
Most popular
Flight

$283

Average price

Cheapest

$458

Average price

33h 55m

Average total duration

33h 25m

Onboard

+

30m

Additional time*

8h 55m

Average total duration

Fastest

5h 55m

Onboard

+

3h 0m

Additional time*

Direct Options

Direct Options

Compare prices and tickets Des Moines, IA to Jacksonville, FL by bus or flight

Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

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Apr 04
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Journey information

Overview: Bus from Des Moines, IA to Jacksonville, FL

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Buses from Des Moines, IA to Jacksonville, FL run on average 1 times per day, taking around 33h 25m. Cheap bus tickets for this journey start at $283 (€231) if you book in advance.

The earliest bus runs at 05:30, the last at 21:40. The fastest bus covers the 1024 miles (1648 km) distance in 33h 25m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
1024 miles (1648 km)
Average bus duration
33h 25m
Cheapest ticket price
$283 (€231)
Buses per day
1
Fastest bus
33h 25m
First bus
5:30 AM
Last bus
9:40 PM
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

FAQs: Bus from Des Moines, IA to Jacksonville, FL

Find answers to the most common questions about traveling from Des Moines, IA to Jacksonville, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Jacksonville, FL, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Des Moines, IA to Jacksonville, FL can start from as little as $283 (€231) when you book in advance. The average bus ticket price for Des Moines, IA to Jacksonville, FL is $283 (€231) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Des Moines, IA to Jacksonville, FL is 33h 25m to travel the 1024 miles (1648 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Des Moines, IA to Jacksonville, FL leaves at 5:30 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Des Moines, IA to Jacksonville, FL leaves at 9:40 PM.
A trip to Jacksonville, FL from Des Moines, IA is worth doing but not as a day trip with a journey time of 33h 25m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Des Moines, IA to Jacksonville, FL is July.
It's helpful to compare your options as there are 2 ways to travel between Des Moines, IA and Jacksonville, FL including taking a bus and flight.
No, the bus from Des Moines, IA to Jacksonville, FL has no accessibility options.
No, there are no bathrooms on board the bus from Des Moines, IA to Jacksonville, FL.
No, bikes are not allowed on board the bus from Des Moines, IA to Jacksonville, FL.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the bus from Des Moines, IA to Jacksonville, FL.
No, luggage for the bus from Des Moines, IA to Jacksonville, FL needs to be booked in addition.
No, there are no additional luggage options for the bus from Des Moines, IA to Jacksonville, FL.
Unfortunately, pets are not allowed on the bus from Des Moines, IA to Jacksonville, FL.
No, there are no USB plugs on board the bus from Des Moines, IA to Jacksonville, FL.
No, there is no WiFi on board the bus from Des Moines, IA to Jacksonville, FL.
Since neither Des Moines, IA nor Jacksonville, FL are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Jacksonville, FL, travelers should be cautious of pickpocketing and vehicle break-ins, especially in crowded areas and popular tourist spots. Common scams include overcharging by unlicensed taxi or ride-share drivers and fake ticket sellers near attractions. Staying aware of surroundings, using reputable transportation services, and avoiding isolated areas at night can help ensure safety.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from Des Moines, IA to Jacksonville, FL

Des Moines
Jacksonville
Jacksonville, JTA Intercity Bus Terminal Bay 6 - 1111 W. Forsyth St
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