Des Moines, IA to San Diego, CA bus

Sat, Apr 04
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FlixBus
Alsa
BlaBlaCar Bus
Costa Verde
Rede Expressos
2,000+ travel companies
FlixBus
Alsa
BlaBlaCar Bus
Costa Verde
Rede Expressos
2,000+ travel companies
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Travel Information

Compare bus and flight for Des Moines, IA to San Diego, CA

Omio recommends booking the flight as it is the most popular option from Des Moines, IA to San Diego, CA among Omio's users. If you are prioritising price take the bus with prices starting from $258. For those with little time consider booking a flight which can get you there in 4h 38m. The ticket price range depends on the travel mode: a bus costs an average of $258, and a flight costs an average of $353.

Distance: 1428 miles (2299 km)

Compare bus with

Bus
Most popular
Flight

$258

Average price

Cheapest

$353

Average price

53h 30m

Average total duration

53h 0m

Onboard

+

30m

Additional time*

7h 38m

Average total duration

Fastest

4h 38m

Onboard

+

3h 0m

Additional time*

Direct Options

Direct Options

Compare prices and tickets Des Moines, IA to San Diego, CA by bus or flight

Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

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Journey information

Overview: Bus from Des Moines, IA to San Diego, CA

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Buses from Des Moines, IA to San Diego, CA run on average 5 times per day, taking around 53h 0m. Cheap bus tickets for this journey start at $258 (€210) if you book in advance.

The earliest bus runs at 05:30, the last at 19:35. The fastest bus covers the 1428 miles (2299 km) distance in 53h 0m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
1428 miles (2299 km)
Average bus duration
53h 0m
Cheapest ticket price
$258 (€210)
Buses per day
5
Fastest bus
53h 0m
First bus
5:30 AM
Last bus
7:35 PM
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

FAQs: Bus from Des Moines, IA to San Diego, CA

Find answers to the most common questions about traveling from Des Moines, IA to San Diego, CA by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at San Diego, CA, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Des Moines, IA to San Diego, CA can start from as little as $258 (€210) when you book in advance. The average bus ticket price for Des Moines, IA to San Diego, CA is $258 (€210) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Des Moines, IA to San Diego, CA is 53h 0m to travel the 1428 miles (2299 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Des Moines, IA to San Diego, CA leaves at 5:30 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Des Moines, IA to San Diego, CA leaves at 7:35 PM.
A trip to San Diego, CA from Des Moines, IA is worth doing but not as a day trip with a journey time of 53h 0m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Des Moines, IA to San Diego, CA is December.
It's helpful to compare your options as there are 2 ways to travel between Des Moines, IA and San Diego, CA including taking a bus and flight.
No, the bus from Des Moines, IA to San Diego, CA has no accessibility options.
No, there are no bathrooms on board the bus from Des Moines, IA to San Diego, CA.
Some of the most interesting sights to explore in San Diego, CA are:
  • Balboa Park, a sprawling urban park with museums, gardens, and the San Diego Zoo
  • USS Midway Museum, a historic naval aircraft carrier museum offering interactive exhibits and tours
  • La Jolla Cove, a picturesque coastal area known for its stunning views and marine life
  • Gaslamp Quarter, a lively historic district with Victorian architecture, dining, and entertainment options
  • Coronado Beach, a beautiful sandy beach known for its gentle waves and iconic hotel.
The best things to do in San Diego, CA include:
  • Explore the vibrant art scene at the Museum of Contemporary Art San Diego
  • enjoy a harbor cruise for stunning views of the skyline and naval ships
  • hike the scenic trails at Torrey Pines State Natural Reserve
  • visit the Birch Aquarium to learn about marine life and ocean conservation
  • experience the thrill of a whale watching tour off the coast.
No, bikes are not allowed on board the bus from Des Moines, IA to San Diego, CA.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the bus from Des Moines, IA to San Diego, CA.
No, luggage for the bus from Des Moines, IA to San Diego, CA needs to be booked in addition.
No, there are no additional luggage options for the bus from Des Moines, IA to San Diego, CA.
Unfortunately, pets are not allowed on the bus from Des Moines, IA to San Diego, CA.
No, there are no USB plugs on board the bus from Des Moines, IA to San Diego, CA.
No, there is no WiFi on board the bus from Des Moines, IA to San Diego, CA.
Since neither Des Moines, IA nor San Diego, CA are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the flight as it is the most popular way to get from Des Moines, IA to San Diego, CA among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In San Diego, CA, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like beaches, public transportation, and popular tourist spots such as the Gaslamp Quarter and Old Town. Common scams include overpriced parking fees and unauthorized ticket sellers near attractions. Staying aware of surroundings, securing belongings, and using official transportation services help reduce risks. Additionally, travelers should avoid isolated areas at night and be mindful of local traffic laws when using scooters or bikes.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from Des Moines, IA to San Diego, CA

Des Moines
San Diego
San Diego, Congress Street (Old Town Park)
information
San Diego, West Harbor Drive (The Headquarters at Seaport District)
information
San Diego, San Ysidro Transit Center
information

More options for your journey from Des Moines, IA to San Diego, CA

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Most popular buses to and from San Diego, CA and Des Moines, IA

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