Travel Information
Compare bus and flight for Des Moines, IA to Orlando, FL
Omio recommends booking the bus as it is the most popular option from Des Moines, IA to Orlando, FL among Omio's users. If you are prioritising price take the bus with prices starting from $133. For those with little time consider booking a flight which can get you there in 3h 28m. The ticket price range depends on the travel mode: a bus costs an average of $133, and a flight costs an average of $169.
Distance: 1134 miles (1826 km)
Compare bus with
Most popular Bus | Flight |
|---|---|
$302 Average price Cheapest | $452 Average price |
33h 0m Average total duration 32h 30m Onboard + 30m Additional time* | 6h 28m Average total duration Fastest 3h 28m Onboard + 3h 0m Additional time* |
![]() Most popular bus company | ![]() Most popular airline |
Direct Options | Direct Options |
Compare prices and tickets Des Moines, IA to Orlando, FL by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Des Moines, IA to Orlando, FL buses with Omio?
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Greyhound to find the best option for your trip from Des Moines, IA to Orlando, FL.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus and flight to ensure you get the best deal for traveling from Des Moines, IA to Orlando, FL.
Why book with Omio over Wanderu or Trainline?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Greyhound to find the best option for your trip from Des Moines, IA to Orlando, FL.
- Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from Des Moines, IA to Orlando, FL.
Journey information
Overview: Bus from Des Moines, IA to Orlando, FL
Buses from Des Moines, IA to Orlando, FL run on average 2 times per day, taking around 32h 30m. Cheap bus tickets for this journey start at $133 (€109) if you book in advance.
The earliest bus runs at 04:45, the last at 23:40. The fastest bus covers the 1134 miles (1826 km) distance in 33h 55m.
Distance 1134 miles (1826 km) |
Average bus duration 32h 30m |
Cheapest ticket price $133 (€109) |
Buses per day 2 |
Fastest bus 33h 55m |
First bus 4:45 AM |
Last bus 11:40 PM |
Bus providers: FlixBus, Greyhound from Des Moines, IA to Orlando, FLYou can travel by bus between Des Moines, IA to Orlando, FL with FlixBus, Greyhound for as low as $133 (€109). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Greyhound
FAQs: Bus from Des Moines, IA to Orlando, FL
Find answers to the most common questions about traveling from Des Moines, IA to Orlando, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Orlando, FL, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Walt Disney World Resort, a massive entertainment complex featuring theme parks, water parks, and resorts
- Universal Orlando Resort, a popular destination with thrilling rides, shows, and attractions based on movies and TV shows
- SeaWorld Orlando, a marine-themed park offering animal exhibits, shows, and rides
- Kennedy Space Center Visitor Complex, an educational attraction showcasing NASA's space exploration history and offering interactive exhibits
- Leu Gardens, a beautiful botanical garden with a variety of plant collections and scenic landscapes.
- ICON Park, a vibrant entertainment complex with dining, shopping, and the iconic Wheel for panoramic views
- Explore the vibrant nightlife and live entertainment at Church Street District
- Enjoy a day of shopping and dining at The Mall at Millenia
- Experience the natural beauty and wildlife at Wekiwa Springs State Park
- Visit the Orlando Science Center for interactive exhibits and planetarium shows.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Greyhound
- $15 per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Des Moines, IA to Orlando, FL
Most popular bus connections from Des Moines, IA
More options for your journey from Des Moines, IA to Orlando, FL
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