Compare prices and tickets Des Moines, IA to Memphis, TN by bus
Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Bus from Des Moines, IA to Memphis, TN
Buses from Des Moines, IA to Memphis, TN run on average 2 times per day, taking around 22h 25m. Cheap bus tickets for this journey start at $249 (€203) if you book in advance.
The earliest bus runs at 05:30, the last at 18:40. The fastest bus covers the 485 miles (781 km) distance in 22h 25m.
Distance 485 miles (781 km) |
Average bus duration 22h 25m |
Cheapest ticket price $249 (€203) |
Buses per day 2 |
Fastest bus 22h 25m |
First bus 5:30 AM |
Last bus 6:40 PM |
Bus providers: Jefferson Lines from Des Moines, IA to Memphis, TNYou can travel by bus between Des Moines, IA to Memphis, TN with Jefferson Lines for as low as $249 (€203). When you search for schedules and tickets, Omio will show you the best journey
Jefferson Lines
FAQs: Bus from Des Moines, IA to Memphis, TN
Find answers to the most common questions about traveling from Des Moines, IA to Memphis, TN by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Memphis, TN, this guide helps you travel smarter and with confidence.

- Graceland, the iconic mansion and former home of Elvis Presley offering tours and exhibits
- Beale Street, a historic street known for its vibrant nightlife and live music venues
- National Civil Rights Museum, a museum located at the former Lorraine Motel, site of Martin Luther King Jr.'s assassination, exploring the history of the civil rights movement
- Memphis Zoo, a popular attraction featuring a wide variety of animal exhibits and conservation programs
- Stax Museum of American Soul Music, a museum celebrating the legacy of soul music and its artists.
- Visit Shelby Farms Park, one of the largest urban parks in America, offering outdoor activities like biking and paddle boating
- Explore the Memphis Botanic Garden, featuring beautiful themed gardens and seasonal events
- Take a riverboat cruise on the Mississippi River for scenic views and historical insights
- Enjoy a live performance at the Orpheum Theatre, a historic venue hosting Broadway shows and concerts
- Discover the vibrant art scene at the Dixon Gallery and Gardens, showcasing fine art and horticulture.
popular bus stations
Popular bus stations from Des Moines, IA to Memphis, TN
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