The cheapest and fastest buses from Rome to Santander
Cheapest price
$243
Average price
$256
Fastest journey
1 d 11 h 25 m
Average duration
1 d 13 h 40 m
Buses per day
2
Distance
1341 km
The best way to find a cheap bus ticket from Rome to Santander is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Rome to Santander will cost around $256 if you buy it on the day, but the cheapest tickets can be found for only $243.
It's difficult to get from Rome to Santander without transferring at least 2 times.
FlixBus · FlixBus · FlixBus5:25 PM39h55Roma, Autostazione (Metro Anagnina)9:20 AMSantander, Estación de Autobuses$2431One-way2 transfers
FlixBus · FlixBus · FlixBus · FlixBus9:55 PM35h25Roma, Autostazione Tiburtina9:20 AMSantander, Estación de Autobuses$2681One-way3 transfers
FlixBus · FlixBus · FlixBus · FlixBus9:55 PM35h25Roma, Autostazione Tiburtina9:20 AMSantander, Estación de Autobuses$2681One-way3 transfers
FlixBus · FlixBus · FlixBus5:25 PM39h55Roma, Autostazione (Metro Anagnina)9:20 AMSantander, Estación de Autobuses$2431One-way2 transfers
Travel Information
Compare bus and flight for Rome to Santander
Omio recommends booking the flight as it is the most popular option from Rome to Santander among Omio's users. If you are prioritising price take the bus with prices starting from $104. For those with little time consider booking a flight which can get you there in 3h 2m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 1.3 - 3.4kg. The ticket price range depends on the travel mode: a bus costs an average of $104, and a flight costs an average of $88.
Distance: 833 miles (1341 km)
Compare bus with
| Bus | Most popular Flight |
|---|---|
$185 Average price Cheapest | $219 Average price |
40h 8m Average total duration 39h 38m Onboard + 30m Additional time* | 6h 2m Average total duration Fastest 3h 2m Onboard + 3h 0m Additional time* |
1.3 - 3.4kg CO2 emissions Lowest | 4.0 - 8.0kg CO2 emissions |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Rome to Santander Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 05:25PM | Arrival Time 09:20AM | Duration 39h55 | Departure days Wed, Thu, Fri | Cheapest price $232 |
Operator FlixBus | Departure Time 09:55PM | Arrival Time 09:20AM | Duration 35h25 | Departure days Wed, Thu, Fri | Cheapest price $233 |
Live departures
Rome to Santander bus times
The table below shows live departures for Rome to Santander buses for today, Wednesday, April 1. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus · FlixBus | 3:25 PM Roma, Autostazione (Metro Anagnina) | 39h55 | 7:20 AM Santander, Estación de Autobuses | 2 transfers | |
FlixBus · FlixBus · FlixBus · FlixBus | 7:55 PM Roma, Autostazione Tiburtina | 35h25 | 7:20 AM Santander, Estación de Autobuses | 3 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Rome to Santander by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Bus from Rome to Santander
Buses from Rome to Santander run on average 2 times per day, taking around 39h 38m. Cheap bus tickets for this journey start at $104 (€84) but you can travel from only $88 (€72) by flight.
The earliest bus runs at 03:00, the last at 22:45. The fastest bus covers the 833 miles (1341 km) distance in 35h 15m.
Distance 833 miles (1341 km) |
Average bus duration 39h 38m |
Cheapest ticket price $104 (€84) |
Buses per day 2 |
Fastest bus 35h 15m |
First bus 3:00 AM |
Last bus 10:45 PM |
FAQs: Bus from Rome to Santander
Find answers to the most common questions about traveling from Rome to Santander by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Santander, this guide helps you travel smarter and with confidence.

- Palacio de la Magdalena, a historic royal palace set on a peninsula offering stunning views and guided tours
- Centro Botín, a modern art center designed by Renzo Piano featuring exhibitions and cultural events
- Playa del Sardinero, a popular beach known for its golden sands and vibrant promenade
- Museo Marítimo del Cantábrico, a maritime museum showcasing marine life and naval history
- Jardines de Piquío, beautifully landscaped gardens offering a peaceful retreat with ocean views.
- Santander Cathedral, a Gothic-style cathedral with impressive architecture and historical significance
- Parque de Mataleñas, a scenic park ideal for hiking and enjoying nature
- Mercado de la Esperanza, a bustling market where you can experience local culture and cuisine
- Paseo de Pereda, a picturesque promenade perfect for a leisurely stroll along the waterfront
- Gran Casino del Sardinero, a historic casino offering entertainment and a glimpse into the city's glamorous past.
popular bus stations
Popular bus stations from Rome to Santander
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