Travel Information
Compare bus, train, and flight for Wiesloch to Prague
Omio recommends booking the train as it is the most popular option from Wiesloch to Prague among Omio's users. If you are prioritising price take the bus with prices starting from €22. For those with little time consider booking a flight which can get you there in 5h 10m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a bus costs an average of €22, and a flight costs an average of €128.
Distance: 261 miles (421 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
€29 Average price Cheapest | €62 Average price | €136 Average price |
6h 30m Average total duration 6h 0m Onboard + 30m Additional time* | 8h 30m Average total duration 8h 0m Onboard + 30m Additional time* | 8h 10m Average total duration Fastest 5h 10m Onboard + 3h 0m Additional time* |
0.4 - 1.1kg CO2 emissions | 0.1 - 0.4kg CO2 emissions Lowest | 1.3 - 2.5kg CO2 emissions |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Compare prices and tickets Wiesloch to Prague by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Bus from Wiesloch to Prague
Buses from Wiesloch to Prague run on average 7 times per day, taking around 6h 0m. Cheap bus tickets for this journey start at $27 (€22) if you book in advance.
There are 4 buses per day. The earliest bus runs at 05:30, the last at 23:05. The fastest bus covers the 261 miles (421 km) distance in 6h 50m.
Distance 261 miles (421 km) |
Average bus duration 6h 0m |
Cheapest ticket price $27 (€22) |
Buses per day 7 |
Direct buses 4 |
Fastest bus 6h 50m |
First bus 05:30 |
Last bus 23:05 |
Bus providers: BlaBlaCar, BlaBlaCar Bus from Wiesloch to PragueYou can travel by bus between Wiesloch to Prague with BlaBlaCar, BlaBlaCar Bus for as low as $27 (€22). When you search for schedules and tickets, Omio will show you the best journey
BlaBlaCar Bus
BlaBlaCar
FAQs: Bus from Wiesloch to Prague
Find answers to the most common questions about traveling from Wiesloch to Prague by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

- Prague Castle, a historic complex and the official office of the Czech president offering panoramic city views
- Charles Bridge, a 14th-century stone bridge adorned with statues and connecting the Old Town with Lesser Town
- Old Town Square, a vibrant historic square featuring the Astronomical Clock and Gothic churches
- St. Vitus Cathedral, a stunning Gothic cathedral known for its impressive architecture and stained glass windows
- The Jewish Quarter, a historic area with preserved synagogues and the Old Jewish Cemetery.
- Petrin Hill, a lush park providing panoramic views of the city and home to the Petrin Tower and Mirror Maze
- Explore the vibrant nightlife in the Vinohrady district, known for its trendy bars and cafes
- Take a boat cruise on the Vltava River to see Prague's landmarks from a different perspective
- Visit the National Museum to delve into Czech history and culture
- Enjoy a classical music concert in one of Prague's historic churches or concert halls.
To find the cheapest bus tickets for your trip from Wiesloch to Prague, follow these tips:
Start your search now and compare ticket prices to find the best deal!
popular bus stations
Popular bus stations from Wiesloch to Prague
- Free Wi-Fi
- Café Na Knížecí (in the station)
- Bistro Praha (0.2 km)
- Restaurace U Knížete (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 137, 176, 191 Metro: B
- 00:00-23:59
- Free Wi-Fi
- Czech Bistro (in the station)
- Fast Food Express (in the station)
- Bohemian Café (0.2 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 135, 175, 207 Metro: C Train: All major s
- 06:00-23:00
- Free Wi-Fi
- Cafeteria Florenc (in the station)
- Bistro Florenc (0.2 km)
- Restaurace U Rozvařilů (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 133, 135, 175, 207 Metro: B, C
More options for your journey from Wiesloch to Prague
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