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The cheapest and fastest trains from Florence Santa Maria Novella to Palermo Centrale
Showing times and prices for Apr 05
Cheapest price
$99
Average price
$125
Fastest journey
12 h 44 m
Average duration
15 h 22 m
Trains per day
6
Distance
655 km
Cheap tickets
The best way to find a cheap train ticket from Florence Santa Maria Novella to Palermo Centrale is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Florence Santa Maria Novella to Palermo Centrale will cost around $125 if you buy it on the day, but the cheapest tickets can be found for only $99.
Fast trains
It's difficult to get from Florence Santa Maria Novella to Palermo Centrale without transferring at least once.
Regionale 18783+
Intercity 594+
InterCityNotte 19596:22 PM17h33Florence Santa Maria Novella11:55 AMPalermo Centrale$991One-way2 transfers
FRECCIAROSSA 9435+InterCityNotte 19598:48 PM15h07Florence Santa Maria Novella11:55 AMPalermo Centrale$1081One-way1 transfer- ETRUSCHI LINE 18255+Intercity 501 · Intercity 7275:27 AM17h31Florence Santa Maria Novella10:58 PMPalermo Centrale$1091One-way2 transfers
- FRECCIAROSSA 9519+Intercity 72710:14 AM12h44Florence Santa Maria Novella10:58 PMPalermo Centrale$1331One-way1 transfer
- Regionale 18251+InterCityNotte 799+Intercity 72312:40 AM18h25Florence Santa Maria Novella7:05 PMPalermo Centrale$1461One-way2 transfers
- FRECCIAROSSA 9519+Intercity 72710:14 AM12h44Florence Santa Maria Novella10:58 PMPalermo Centrale$1331One-way1 transfer
- FRECCIAROSSA 1000 9555+InterCityNotte 19557:14 PM13h54Florence Santa Maria Novella9:08 AMPalermo Centrale$1561One-way1 transfer
- FRECCIAROSSA 9435+InterCityNotte 19598:48 PM15h07Florence Santa Maria Novella11:55 AMPalermo Centrale$1081One-way1 transfer
- ETRUSCHI LINE 18255+Intercity 501 · Intercity 7275:27 AM17h31Florence Santa Maria Novella10:58 PMPalermo Centrale$1091One-way2 transfers
- Regionale 18783+Intercity 594+InterCityNotte 19596:22 PM17h33Florence Santa Maria Novella11:55 AMPalermo Centrale$991One-way2 transfers
Travel Information
Compare train, bus, flight, and ferry for Florence Santa Maria Novella to Palermo Centrale
Omio recommends booking the train as it is the most popular option from Florence Santa Maria Novella to Palermo Centrale among Omio's users. If you are prioritising price take the bus with prices starting from $18. For those with little time consider booking a flight which can get you there in 1h 43m. The ticket price range depends on the travel mode: a bus costs an average of $18, and a train costs an average of $83.
Distance: 406 miles (655 km)
Compare train with
Most popular Train | Bus | Flight | Ferry |
|---|---|---|---|
$136 Average price | $56 Average price Cheapest | $109 Average price | $65 Average price |
13h 12m Average total duration 12h 42m Onboard + 30m Additional time* | 16h 47m Average total duration 16h 17m Onboard + 30m Additional time* | 4h 43m Average total duration Fastest 1h 43m Onboard + 3h 0m Additional time* | 21h 0m Average total duration 20h 0m Onboard + 1h 0m Additional time* |
Most popular train company |  Most popular bus company |  Most popular airline |  Most popular ferry company |
Direct Options | Direct Options | Direct Options | Direct Options |
Live departures
Florence Santa Maria Novella to Palermo Centrale train times
The table below shows live departures for Florence Santa Maria Novella to Palermo Centrale trains for today, Saturday, April 4. You can also manually refresh the results below to see updated train journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| Regionale 18251+InterCityNotte 799+Intercity 723 | 10:40 PM Florence Santa Maria Novella | 18h25 | 5:05 PM Palermo Centrale | 2 transfers | |
| Sunday, April 5 | |||||
| ETRUSCHI LINE 18255+Intercity 501 · Intercity 727 | 3:27 AM Florence Santa Maria Novella | 17h31 | 8:58 PM Palermo Centrale | 2 transfers | |
| FRECCIAROSSA 9519+Intercity 727 | 8:14 AM Florence Santa Maria Novella | 12h44 | 8:58 PM Palermo Centrale | 1 transfer | |
| Regionale 18783+Intercity 594+InterCityNotte 1959 | 4:22 PM Florence Santa Maria Novella | 17h33 | 9:55 AM Palermo Centrale | 2 transfers | |
| FRECCIAROSSA 1000 9555+InterCityNotte 1955 | 5:14 PM Florence Santa Maria Novella | 13h54 | 7:08 AM Palermo Centrale | 1 transfer | |
| FRECCIAROSSA 9435+InterCityNotte 1959 | 6:48 PM Florence Santa Maria Novella | 15h07 | 9:55 AM Palermo Centrale | 1 transfer | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Florence Santa Maria Novella to Palermo Centrale by train, bus, flight, or ferry
Compare train, bus, flight, and ferry prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Florence Santa Maria Novella to Palermo Centrale trains with Omio?
Intercity Notte as well as Intercity, Italo, Frecciargento, Frecciarossa and more offer trains services from Florence Santa Maria Novella to Palermo Centrale.
Omio is the only official third party seller for Intercity Notte tickets.
Why book with Omio vs Intercity Notte?
- Compare with other providers: On Omio, you can not only buy tickets for Intercity Notte, but also compare tickets for the likes of Intercity, Italo, Frecciargento or Frecciarossa to find the best option for your trip from Florence Santa Maria Novella to Palermo Centrale.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Intercity Notte with all available travel options, which are train, bus, flight and ferry to ensure you get the best deal for traveling from Florence Santa Maria Novella to Palermo Centrale.
Journey information
Overview: Train from Florence Santa Maria Novella to Palermo Centrale
ItalyItaly
Trains from Florence Santa Maria Novella to Palermo Centrale run on average 6 times per day, taking around 12h 42m. Cheap train tickets for this journey start at $83 (€68) but you can travel from only $18 (€15) by bus.
The earliest train runs at 04:35, the last at 23:40. The fastest train covers the 406 miles (655 km) distance in 15h 9m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $18 (€15)
Distance 406 miles (655 km) |
Average train duration 12h 42m |
Cheapest ticket price $83 (€68) |
Trains per day 6 |
Fastest train 15h 9m |
First train 4:35 AM |
Last train 11:40 PM |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $18 (€15)
Train companies: Intercity Notte, Intercity, Italo, Frecciargento, Frecciarossa from Florence Santa Maria Novella to Palermo Centrale trainsIntercity Notte, Intercity, Italo, Frecciargento, Frecciarossa trains will get you between Florence Santa Maria Novella and Palermo Centrale from $18 (€15). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Intercity Notte
About
Intercity Notte is an Italian train service operated by Trenitalia. It runs overnight services between major cities in Italy, making it a great option for travelers looking to save time and money. The Intercity Notte offers two types of trains: the Frecciarossa Notte and the Frecciargento Notte. The Frecciarossa Notte is the fastest train, with speeds of up to 300 km/h, while the Frecciargento Notte is slightly slower but still offers a comfortable journey. Both trains offer a range of onboard facilities, including comfortable seating, air conditioning, and Wi-Fi. Trenitalia offers a range of ticket types, including Standard, Comfort, and Business. Standard tickets are the most affordable, while Comfort and Business tickets offer additional benefits such as priority boarding and access to the lounge. The most popular routes for Intercity Notte are Rome to Milan, Rome to Venice, and Milan to Venice. These routes offer travelers the chance to explore some of Italy's most iconic cities in a convenient and comfortable way.
Luggage & cancellation policy
Intercity Notte frequency
2 a day
Luggage included
1 handbag and 1 suitcase included in ticket price
Luggage storage
Luggage racks above seats and at carriage ends
Cancellation Policy
Cancellation possible according to ticket type conditions
Refund
Full refund provided for canceled trains
Amenities on board the train
Wifi
Food sold onboard
Restaurant car with full dining service and bar
Seat reservation
Seat reservation included in ticket price
Toilets
USB plugs
Accessibility
Wheelchair spaces and assistance available for disabled passengers
Pets
Small pets in carriers travel free. Larger dogs require paid ticket and muzzle. Guide dogs free.
Quiet zone
Intercity
About
Trenitalia Intercity is a high-speed train service operated by the Italian national railway company, Trenitalia. It operates throughout the country, with services running from early morning to late evening. The Intercity trains come in two types: the Intercity Plus, which is the fastest and most comfortable, and the Intercity, which is slightly slower but still offers a comfortable journey. Onboard facilities include air conditioning, power sockets, Wi-Fi, and a bar service. There are several ticket types available, including Standard, Super Economy, and Business. The most popular routes for Trenitalia Intercity are from Rome to Milan, Naples to Florence, and Turin to Venice.
Luggage & cancellation policy
Average Duration
17h 16m
Cheapest Price
$83 (€68)
Luggage included
2 pieces of luggage up to 30kg total
Luggage storage
Overhead racks and designated luggage areas at end of carriages
Cancellation Policy
According to ticket conditions
Refund
Full refund provided
Amenities on board the train
Wifi
Food sold onboard
Restaurant car with hot meals and snacks, trolley service in some trains. But do not count on the presence of a buffet car. So if having access to food and drink on the train is important to you, it’s best to bring your own refreshments onboard.
Seat reservation
Seat reservation included in ticket price for most routes
Toilets
USB plugs
Accessibility
Wheelchair spaces and accessible toilets available
Pets
Small pets in carriers allowed free, larger dogs require paid ticket
Quiet zone
Italo
About
Italo is Italy’s private high-speed train service operated by Nuovo Trasporto Viaggiatori (NTV), connecting major cities such as Rome, Milan, Naples, Florence, Turin, Bologna, and Salerno. Its fleet includes the Italo AGV 575, capable of speeds up to 186 mph (300 km/h), and the eco-friendly Italo EVO, which reaches up to 150 mph (250 km/h). Passengers can choose from four classes — Smart, Comfort, Prima, and Club Executive — all offering modern amenities such as free Wi-Fi, power outlets, reclining leather seats, footrests, bathrooms, snack machines, and Italo Live entertainment with movies, music, and games. Italo offers three fare types — Low Cost, Economy, and Flex — providing different levels of price and flexibility. Popular routes include Rome–Milan, Rome–Florence, and Milan–Turin, making Italo a fast, comfortable, and convenient way to travel around Italy.
Luggage & cancellation policy
Average Duration
14h 7m
Cheapest Price
$129 (€105)
Italo frequency
1 a day
Luggage included
2 pieces of hand luggage (max 55x35x25cm) and 1 piece of luggage (max 75x53x30cm)
Luggage storage
Overhead racks and designated luggage areas between seats
Cancellation Policy
Cancellation possible according to ticket conditions
Refund
Full refund provided for canceled trains
Amenities on board the train
Wifi
Food sold onboard
Snack bar service available in most trains with drinks and light refreshments. Welcome service in Prima and Club Executive classes
Seat reservation
Included in Prima and Club Executive. Optional extra cost in Smart and Comfort
Toilets
USB plugs
Accessibility
Wheelchair spaces and assistance available for passengers with reduced mobility
Pets
Small pets in carriers travel free. Larger dogs require paid ticket and muzzle. Guide dogs travel free
Quiet zone
Frecciargento
About
Frecciargento is a high-speed train service operated by Trenitalia, the national railway company of Italy. It runs on the most popular routes throughout the country, connecting major cities such as Rome, Milan, Florence, and Venice. Frecciargento trains offer a comfortable and convenient way to travel, with a range of ticket types available, including Economy, Standard, and Business. Onboard facilities include air-conditioning, power sockets, and free Wi-Fi. Frecciargento trains are fast and reliable, with journey times of up to four hours between Rome and Milan. They are a great way to explore Italy in style and comfort.
Luggage & cancellation policy
Frecciargento frequency
1 a day
Luggage included
1 carry-on bag and 1 piece of luggage included
Luggage storage
Overhead racks, luggage areas at end of carriages, between seats
Cancellation Policy
Cancellation possible according to fare conditions
Refund
Full refund provided for canceled trains
Amenities on board the train
Wifi
Food sold onboard
Bar-bistro service with snacks, drinks, and light meals. At-seat service in First Class
Seat reservation
Seat reservation included in ticket price for all classes
Toilets
USB plugs
Accessibility
Wheelchair spaces, accessible toilets, assistance service available
Pets
Small pets in carriers travel free. Larger dogs require paid ticket and muzzle. Guide dogs travel free
Quiet zone
Frecciarossa
About
Step on board a Frecciarossa train and relax as you travel across Italy. Trenitalia’s Frecciarossa high-speed trains make around 200 connections across the country each day and are renowned for their comfort, speed, and reduced environmental impact. Reaching speeds of up to 186 mph (300 km/h), they connect major destinations such as Rome, Florence, Milan, Venice, and Naples quickly and efficiently. When booking your Frecciarossa journey, you can choose between four classes: Standard, Premium, Business, and Executive. While each class offers different levels of comfort, all provide free Wi-Fi access, power outlets, air conditioning, bathrooms, luggage storage, onboard entertainment, and restaurant and bar services. Ticket options include Super Economy, Economy, and Base, making it easy to find the right balance of comfort and price for your trip.
Luggage & cancellation policy
Average Duration
15h 9m
Cheapest Price
$102 (€83)
Frecciarossa frequency
1 a day
Luggage included
1 carry-on bag and 1 suitcase per passenger
Luggage storage
Overhead racks, dedicated luggage areas at carriage ends, under seats
Cancellation Policy
Refund policy depends on ticket type
Refund
Full refund provided for canceled trains
Amenities on board the train
Wifi
Food sold onboard
Restaurant car with full meals, bar service with snacks and beverages, at-seat service in Executive class
Seat reservation
Included in Executive class, optional fee for other classes
Toilets
USB plugs
Accessibility
Wheelchair spaces, accessible toilets, assistance service available
Pets
Small pets in carriers travel free, larger dogs require paid ticket and muzzle, service animals free
Quiet zone
FAQs: Trains from Florence Santa Maria Novella to Palermo Centrale
Find answers to the most common questions about traveling from Florence Santa Maria Novella to Palermo Centrale by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Palermo Centrale, this guide helps you travel smarter and with confidence.
Train ticket prices from Florence Santa Maria Novella to Palermo Centrale can vary. The cheapest ticket starts at $83 (€68), while the average price is around $136 (€111).
The train from Florence Santa Maria Novella to Palermo Centrale takes 15h 9m and runs 6 per day.
The first train from Florence Santa Maria Novella to Palermo Centrale leaves at 4:35 AM.
The distance by train from Florence Santa Maria Novella to Palermo Centrale is 406 miles (655 km).
The last train from Florence Santa Maria Novella to Palermo Centrale leaves at 11:40 PM.
Yes, there is a high-speed train from Florence Santa Maria Novella to Palermo Centrale.
There is no direct train service currently available from Florence Santa Maria Novella to Palermo Centrale.
Yes, there is a night train from Florence Santa Maria Novella to Palermo Centrale.
The cheapest way to get from Florence Santa Maria Novella to Palermo Centrale is by bus, with a cost of around $18 (€15).
The train journey from Firenze Santa Maria Novella to Palermo Centrale is scenic, offering views of the Tuscan countryside, the dramatic Apennine Mountains, and the beautiful coastline of southern Italy as you approach Sicily.
A day trip from Firenze Santa Maria Novella to Palermo Centrale is not feasible as the journey takes 15h 9m one way. There are 6 train trips available per day.
Yes, you can take the train from Florence Santa Maria Novella to Palermo Centrale.
Since both Florence Santa Maria Novella and Palermo Centrale are in the Schengen Area, a passport is not required for European Union (EU) or Schengen-associated country citizens. A national ID card is sufficient.
Popular day trips by train from Palermo Centrale include Cefalù, Santa Flavia, Isola delle Femmine, Campofelice di Roccella, Punta Raisi.
We recommend using the train as it is the most popular way to get from Florence Santa Maria Novella to Palermo Centrale among Omio's users.
Items not allowed on trains typically include hazardous materials such as explosives, flammable liquids, corrosive substances, and illegal drugs. Additionally, large or bulky items that may obstruct aisles or emergency exits, as well as pets without proper carriers, may be restricted. Specific prohibited items can vary by train operator and region, so please check the rules for your particular journey.
Yes, rail passes such as the Eurail Italy Pass and Interrail Italy Pass are valid on most trains operated by Trenitalia and Italo within Italy, including regional, intercity, and high-speed trains, though some restrictions and seat reservation fees may apply.
Italy uses the euro (EUR) as its currency. Travelers generally find it convenient to use cards for most payments, especially in cities and larger establishments, but carrying some cash is advisable for small shops, markets, and rural areas where card acceptance may be limited.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular train stations
Popular train stations from Florence Santa Maria Novella to Palermo Centrale
Florence
Sicily
Amenities at train station
Wifi
Lockers
Parking
Dining
ATM
Taxis
Accessibility
WC
Hotel
Ticket Office
Bike Parking
Bike Rental
Car Rental
Information Deskinformation
Ticket Office Hours
- Mon - Sun: 06:00 - 21:00
Distance to city center
1 kmWifi
- Free WiFi (30 minutes limit).
Lockers
- Provided by KiPoint and located on the ground floor, on the side of Piazza Adua. Open daily from 06:00 to 23:00.
Dining
- 12oz Coffee Joint
- Casa Maioli
- Don Nino
- Fratelli Cuore
- McDonald´s
- Panella
- Segafredo Zanetti
- Spizzico
- Venchi
- & many more
Accessibility
- Elevators, escalators, step-free access. Mobility assistance is available with the Sala Blu, located next to Platform 1.
Hotel
- Hotel Luxor Florence
- Joy Hotel Florence
- Diplomat Hotel Florence
Ticket Office
- Mon - Sun: 06:00 - 21:00
Information Desk
- Located inside and outside the station.
Public transit options for Firenze Santa Maria Novella
- Tram lines: T1, T2
- Bus lines: 6, 11, 12, 13, 17, 23, 36, 37, C4
- Train lines: FR, FA, Italo
Most popular train connections from Florence Santa Maria Novella
More options for your journey from Florence Santa Maria Novella to Palermo Centrale
Here are some other resources that might have the information you need
Most popular trains to and from Palermo Centrale and Florence Santa Maria Novella
Most popular train connections to Palermo Centrale
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