The cheapest and fastest trains from Milan Centrale to Palermo Centrale
Cheapest price
$146
Average price
$259
Fastest journey
14 h 28 m
Average duration
15 h
Trains per day
65
Distance
890 km
The best way to find a cheap train ticket from Milan Centrale to Palermo Centrale is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Milan Centrale to Palermo Centrale will cost around $259 if you buy it on the day, but the cheapest tickets can be found for only $146.
Of the 65 trains that leave Milan Centrale for Palermo Centrale on Sun, Apr 05, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Apr 05 the direct trains cover the 890 km distance in an average of 15 h but if you time it right, some trains will get you there in just 14 h 28 m .
On Sun, Apr 05 the slowest trains will take 15 h 23 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
InterCityNotte 19638:10 PM20h45Milan Centrale4:55 PMPalermo Centrale$1461One-way0 transfers
FRECCIAROSSA 1000 9613+
Intercity 7278:30 AM14h28Milan Centrale10:58 PMPalermo Centrale$2121One-way1 transfer
Intercity 1549 · Intercity 511+
InterCityNotte 195510:05 AM23h03Milan Centrale9:08 AMPalermo Centrale$2181One-way2 transfers
9971+
Intercity 7277:15 AM15h43Milan Centrale10:58 PMPalermo Centrale$2201One-way1 transfer
9967+
Intercity 7276:15 AM16h43Milan Centrale10:58 PMPalermo Centrale$2201One-way1 transfer
FRECCIAROSSA 1000 9613+
Intercity 7278:30 AM14h28Milan Centrale10:58 PMPalermo Centrale$2121One-way1 transfer
9998+
FRECCIAROSSA 9519+
Intercity 7278:15 AM14h43Milan Centrale10:58 PMPalermo Centrale$2631One-way2 transfers
FRECCIAROSSA 1000 9653+
InterCityNotte 19556:00 PM15h08Milan Centrale9:08 AMPalermo Centrale$2421One-way1 transfer
9917+
FRECCIAROSSA 9519+
Intercity 7277:40 AM15h18Milan Centrale10:58 PMPalermo Centrale$2831One-way2 transfers
9993+
FRECCIAROSSA 1000 9653+
InterCityNotte 19555:45 PM15h23Milan Centrale9:08 AMPalermo Centrale$2931One-way2 transfers
Travel Information
Compare train, bus, flight, and ferry for Milan Centrale to Palermo Centrale
Omio recommends booking the train as it is the most popular option from Milan Centrale to Palermo Centrale among Omio's users. If you are prioritising price take the ferry with prices starting from $75. For those with little time consider booking a flight which can get you there in 1h 42m. The ticket price range depends on the travel mode: a ferry costs an average of $75, and a train costs an average of $73.
Distance: 553 miles (890 km)
Compare train with
Most popular Train | Flight | Bus | Ferry |
|---|---|---|---|
$141 Average price | $117 Average price | $93 Average price | $85 Average price Cheapest |
15h 15m Average total duration 14h 45m Onboard + 30m Additional time* | 4h 42m Average total duration Fastest 1h 42m Onboard + 3h 0m Additional time* | 21h 1m Average total duration 20h 31m Onboard + 30m Additional time* | 21h 23m Average total duration 20h 23m Onboard + 1h 0m Additional time* |
![]() Most popular train company | ![]() Most popular airline | ![]() Most popular bus company | ![]() Most popular ferry company |
Direct Options | Direct Options | Direct Options | Direct Options |
Live departures
Milan Centrale to Palermo Centrale train times
The table below shows live departures for Milan Centrale to Palermo Centrale trains for tomorrow, Saturday, April 4. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
9907+ Intercity 727 | On time 3:40 AM Milan Centrale | 17h18 | 8:58 PM Palermo Centrale | 1 transfer | |
9907+ FRECCIAROSSA 9519+ Intercity 727 | On time 3:40 AM Milan Centrale | 17h18 | 8:58 PM Palermo Centrale | 2 transfers | |
9967+ FRECCIAROSSA 9519+ Intercity 727 | On time 4:15 AM Milan Centrale | 16h43 | 8:58 PM Palermo Centrale | 2 transfers | |
9967+ Intercity 727 | On time 4:15 AM Milan Centrale | 16h43 | 8:58 PM Palermo Centrale | 1 transfer | |
8111+ Intercity 727 | 4:40 AM Milan Centrale | 16h18 | 8:58 PM Palermo Centrale | 1 transfer | |
8111+ FRECCIAROSSA 9519+ Intercity 727 | 4:40 AM Milan Centrale | 16h18 | 8:58 PM Palermo Centrale | 2 transfers | |
9971+ FRECCIAROSSA 9519+ Intercity 727 | On time 5:15 AM Milan Centrale | 15h43 | 8:58 PM Palermo Centrale | 2 transfers | |
9971+ Intercity 727 | On time 5:15 AM Milan Centrale | 15h43 | 8:58 PM Palermo Centrale | 1 transfer | |
9917+ FRECCIAROSSA 9519+ Intercity 727 | On time 5:40 AM Milan Centrale | 15h18 | 8:58 PM Palermo Centrale | 2 transfers | |
9998+ FRECCIAROSSA 9519+ Intercity 727 | On time 6:15 AM Milan Centrale | 14h43 | 8:58 PM Palermo Centrale | 2 transfers | |
FRECCIAROSSA 1000 9613+ Intercity 727 | 6:30 AM Milan Centrale | 14h28 | 8:58 PM Palermo Centrale | 1 transfer | |
9975+ InterCityNotte 1955 | On time 7:15 AM Milan Centrale | 23h53 | 7:08 AM Palermo Centrale | 1 transfer | |
9923+ InterCityNotte 1955 | On time 7:40 AM Milan Centrale | 23h28 | 7:08 AM Palermo Centrale | 1 transfer | |
9923+ FRECCIAROSSA 1000 9653+ InterCityNotte 1955 | On time 7:40 AM Milan Centrale | 23h28 | 7:08 AM Palermo Centrale | 2 transfers | |
Intercity 1549 · Intercity 511+ InterCityNotte 1955 | 8:05 AM Milan Centrale | 23h03 | 7:08 AM Palermo Centrale | 2 transfers | |
9977+ FRECCIAROSSA 1000 9653+ InterCityNotte 1955 | On time 8:15 AM Milan Centrale | 22h53 | 7:08 AM Palermo Centrale | 2 transfers | |
9977+ InterCityNotte 1955 | On time 8:15 AM Milan Centrale | 22h53 | 7:08 AM Palermo Centrale | 1 transfer | |
9927+ FRECCIAROSSA 1000 9653+ InterCityNotte 1955 | On time 8:40 AM Milan Centrale | 22h28 | 7:08 AM Palermo Centrale | 2 transfers | |
9927+ InterCityNotte 1955 | On time 8:40 AM Milan Centrale | 22h28 | 7:08 AM Palermo Centrale | 1 transfer | |
9979+ InterCityNotte 1955 | On time 9:15 AM Milan Centrale | 21h53 | 7:08 AM Palermo Centrale | 1 transfer | |
9979+ FRECCIAROSSA 1000 9653+ InterCityNotte 1955 | On time 9:15 AM Milan Centrale | 21h53 | 7:08 AM Palermo Centrale | 2 transfers | |
9931+ InterCityNotte 1955 | On time 9:40 AM Milan Centrale | 21h28 | 7:08 AM Palermo Centrale | 1 transfer | |
9931+ FRECCIAROSSA 1000 9653+ InterCityNotte 1955 | On time 9:40 AM Milan Centrale | 21h28 | 7:08 AM Palermo Centrale | 2 transfers | |
9931+ InterCityNotte 1959 | On time 9:40 AM Milan Centrale | 24h15 | 9:55 AM Palermo Centrale | 1 transfer | |
9981+ InterCityNotte 1955 | On time 10:20 AM Milan Centrale | 20h48 | 7:08 AM Palermo Centrale | 1 transfer | |
9981+ FRECCIAROSSA 1000 9653+ InterCityNotte 1955 | On time 10:20 AM Milan Centrale | 20h48 | 7:08 AM Palermo Centrale | 2 transfers | |
9981+ InterCityNotte 1959 | On time 10:20 AM Milan Centrale | 23h35 | 9:55 AM Palermo Centrale | 1 transfer | |
9935+ InterCityNotte 1955 | On time 10:40 AM Milan Centrale | 20h28 | 7:08 AM Palermo Centrale | 1 transfer | |
9935+ FRECCIAROSSA 1000 9653+ InterCityNotte 1955 | On time 10:40 AM Milan Centrale | 20h28 | 7:08 AM Palermo Centrale | 2 transfers | |
9935+ InterCityNotte 1959 | On time 10:40 AM Milan Centrale | 23h15 | 9:55 AM Palermo Centrale | 1 transfer | |
9983+ InterCityNotte 1959 | On time 11:20 AM Milan Centrale | 22h35 | 9:55 AM Palermo Centrale | 1 transfer | |
9983+ InterCityNotte 1955 | On time 11:20 AM Milan Centrale | 19h48 | 7:08 AM Palermo Centrale | 1 transfer | |
9983+ FRECCIAROSSA 1000 9653+ InterCityNotte 1955 | On time 11:20 AM Milan Centrale | 19h48 | 7:08 AM Palermo Centrale | 2 transfers | |
9939+ InterCityNotte 1959 | On time 11:40 AM Milan Centrale | 22h15 | 9:55 AM Palermo Centrale | 1 transfer | |
9939+ InterCityNotte 1955 | On time 11:40 AM Milan Centrale | 19h28 | 7:08 AM Palermo Centrale | 1 transfer | |
9939+ FRECCIAROSSA 1000 9653+ InterCityNotte 1955 | On time 11:40 AM Milan Centrale | 19h28 | 7:08 AM Palermo Centrale | 2 transfers | |
Intercity 597 · Intercity 594+ InterCityNotte 1959 | 11:48 AM Milan Centrale | 22h07 | 9:55 AM Palermo Centrale | 2 transfers | |
9985+ FRECCIAROSSA 1000 9653+ InterCityNotte 1955 | On time 12:20 PM Milan Centrale | 18h48 | 7:08 AM Palermo Centrale | 2 transfers | |
9985+ InterCityNotte 1955 | On time 12:20 PM Milan Centrale | 18h48 | 7:08 AM Palermo Centrale | 1 transfer | |
9985+ InterCityNotte 1959 | On time 12:20 PM Milan Centrale | 21h35 | 9:55 AM Palermo Centrale | 1 transfer | |
6143+ FRECCIAROSSA 1000 9653+ InterCityNotte 1955 | 12:40 PM Milan Centrale | 18h28 | 7:08 AM Palermo Centrale | 2 transfers | |
6143+ InterCityNotte 1959 | 12:40 PM Milan Centrale | 21h15 | 9:55 AM Palermo Centrale | 1 transfer | |
6143+ InterCityNotte 1955 | 12:40 PM Milan Centrale | 18h28 | 7:08 AM Palermo Centrale | 1 transfer | |
9987+ InterCityNotte 1959 | On time 1:15 PM Milan Centrale | 20h40 | 9:55 AM Palermo Centrale | 1 transfer | |
9987+ InterCityNotte 1955 | On time 1:15 PM Milan Centrale | 17h53 | 7:08 AM Palermo Centrale | 1 transfer | |
9987+ FRECCIAROSSA 1000 9653+ InterCityNotte 1955 | On time 1:15 PM Milan Centrale | 17h53 | 7:08 AM Palermo Centrale | 2 transfers | |
9947+ FRECCIAROSSA 1000 9653+ InterCityNotte 1955 | On time 1:40 PM Milan Centrale | 17h28 | 7:08 AM Palermo Centrale | 2 transfers | |
9947+ InterCityNotte 1959 | On time 1:40 PM Milan Centrale | 20h15 | 9:55 AM Palermo Centrale | 1 transfer | |
9947+ InterCityNotte 1955 | On time 1:40 PM Milan Centrale | 17h28 | 7:08 AM Palermo Centrale | 1 transfer | |
9989+ InterCityNotte 1959 | On time 2:15 PM Milan Centrale | 19h40 | 9:55 AM Palermo Centrale | 1 transfer | |
9989+ InterCityNotte 1955 | On time 2:15 PM Milan Centrale | 16h53 | 7:08 AM Palermo Centrale | 1 transfer | |
9989+ FRECCIAROSSA 1000 9653+ InterCityNotte 1955 | On time 2:15 PM Milan Centrale | 16h53 | 7:08 AM Palermo Centrale | 2 transfers | |
9951+ FRECCIAROSSA 1000 9653+ InterCityNotte 1955 | On time 2:40 PM Milan Centrale | 16h28 | 7:08 AM Palermo Centrale | 2 transfers | |
9951+ InterCityNotte 1959 | On time 2:40 PM Milan Centrale | 19h15 | 9:55 AM Palermo Centrale | 1 transfer | |
9991+ InterCityNotte 1959 | On time 3:15 PM Milan Centrale | 18h40 | 9:55 AM Palermo Centrale | 1 transfer | |
9991+ FRECCIAROSSA 1000 9653+ InterCityNotte 1955 | On time 3:15 PM Milan Centrale | 15h53 | 7:08 AM Palermo Centrale | 2 transfers | |
9955+ InterCityNotte 1959 | On time 3:40 PM Milan Centrale | 18h15 | 9:55 AM Palermo Centrale | 1 transfer | |
9993+ InterCityNotte 1959 | 3:45 PM Milan Centrale | 18h10 | 9:55 AM Palermo Centrale | 1 transfer | |
9993+ FRECCIAROSSA 1000 9653+ InterCityNotte 1955 | 3:45 PM Milan Centrale | 15h23 | 7:08 AM Palermo Centrale | 2 transfers | |
FRECCIAROSSA 1000 9653+ InterCityNotte 1955 | 4:00 PM Milan Centrale | 15h08 | 7:08 AM Palermo Centrale | 1 transfer | |
9995+ InterCityNotte 1959 | 4:20 PM Milan Centrale | 17h35 | 9:55 AM Palermo Centrale | 1 transfer | |
9959+ InterCityNotte 1959 | On time 4:40 PM Milan Centrale | 17h15 | 9:55 AM Palermo Centrale | 1 transfer | |
9997+ InterCityNotte 1959 | 4:45 PM Milan Centrale | 17h10 | 9:55 AM Palermo Centrale | 1 transfer | |
FRECCIAROSSA 1000 9663+ InterCityNotte 1959 | 5:35 PM Milan Centrale | 16h20 | 9:55 AM Palermo Centrale | 1 transfer | |
InterCityNotte 1963 | 6:10 PM Milan Centrale | 20h45 | 2:55 PM Palermo Centrale | 0 transfersDirect | |
Find all the dates and times for this journey
Compare prices and tickets Milan Centrale to Palermo Centrale by train, bus, flight, or ferry
Compare train, bus, flight, and ferry prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Apr 05
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Apr 22
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Apr 24
Apr 25
Why should you book Milan Centrale to Palermo Centrale trains with Omio?
Why book with Omio vs Intercity Notte?
- Compare with other providers: On Omio, you can not only buy tickets for Intercity Notte, but also compare tickets for the likes of Intercity, Italo, Frecciargento or Frecciarossa to find the best option for your trip from Milan Centrale to Palermo Centrale.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Intercity Notte with all available travel options, which are train, bus, flight and ferry to ensure you get the best deal for traveling from Milan Centrale to Palermo Centrale.
Journey information
Overview: Train from Milan Centrale to Palermo Centrale
Trains from Milan Centrale to Palermo Centrale run on average 7 times per day, taking around 14h 45m. Cheap train tickets for this journey start at $73 (€60) but you can travel from only $21 (€17) by flight.
There are 1 trains per day. The earliest train runs at 07:30, the last at 21:45. The fastest train covers the 553 miles (890 km) distance in 14h 25m.
Distance 553 miles (890 km) |
Average train duration 14h 45m |
Cheapest ticket price $73 (€60) |
Trains per day 7 |
Direct trains 1 |
Fastest train 14h 25m |
First train 7:30 AM |
Last train 9:45 PM |
Train companies: Intercity Notte, Intercity, Italo, Frecciargento, Frecciarossa from Milan Centrale to Palermo Centrale trainsIntercity Notte, Intercity, Italo, Frecciargento, Frecciarossa trains will get you between Milan Centrale and Palermo Centrale from $21 (€17). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Intercity Notte
Intercity
Italo
Frecciargento
Frecciarossa
FAQs: Trains from Milan Centrale to Palermo Centrale
Find answers to the most common questions about traveling from Milan Centrale to Palermo Centrale by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Palermo Centrale, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Milan Centrale to Palermo Centrale
- Mon - Sun: 05:50 - 22:20
- Free WiFi in the station.
- Provided by KiPoint and located on the ground floor, on the side of Piazza Luigi di Savoia. It is open every day from 06:00 to 23:00.
- Venchi
- Panzera Coffee
- Burger King
- Bar Motta
- Caffè Napoli
- VyTA Boulangerie
- Spontini
- Starbucks
- Dispensa Emilia
- McDonald's
- & many more
- Station is wheelchair accessible, has elevators and the Sala Blu, Trenitalia's office of assistance for disabled travelers, is next to Platform 4.
- Glam Hotel Milano
- NYX MIlan
- iQ Hotel Milano
- Mon - Sun: 05:50 - 22:20
- Located next to the ticket office on the ground floor in the shopping gallery.
- Metro lines: M2 (green), M3 (yellow)
- Tram lines: 1
- Bus lines: 5, 9, 10, 42, 81, 87, 152, 728, N26, NM2, NM3, Air Bus, Orio Shuttle
- Train lines: FR, FB, EC, Thello, XP2, R28, IC, ICN, RV, R, Regio, Italo
Most popular train connections from Milan Centrale
More options for your journey from Milan Centrale to Palermo Centrale
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