Travel Information
Compare train, bus, and flight for Mulhouse to Lyon
Omio recommends booking the train as it is the most popular option from Mulhouse to Lyon among Omio's users. If you are prioritising price take the bus with prices starting from $16. For those with little time consider booking a train which can get you there in 3h 15m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.3kg. The ticket price range depends on the travel mode: a bus costs an average of $16, and a train costs an average of $49.
Distance: 181 miles (292 km)
Compare train with
Most popular Train | Bus |
|---|---|
$74 Average price | $33 Average price Cheapest |
3h 45m Average total duration Fastest 3h 15m Onboard + 30m Additional time* | 4h 53m Average total duration 4h 23m Onboard + 30m Additional time* |
0.1 - 0.3kg CO2 emissions Lowest | 0.3 - 0.7kg CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Travel optionsfrom Mulhouse to Lyon
How to get from Mulhouse to Lyon by train, bus or flight.
Our recommendation
The best way to travel from Mulhouse to Lyon is by taking a bus because it’s the best combination of price and speed.
FlixBus7:30 AM5h20Mulhouse, Gare Centrale12:50 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$421One-way0 transfers
Cheapest
FlixBus8:40 PM4h40Mulhouse, Gare Centrale1:20 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$361One-way0 transfers
Fastest
98779:56 AM3h03Mulhouse-Ville12:59 PMLyon Part Dieu$1101One-way0 transfers
Other options
9210+
1777110:56 AM3h48Mulhouse-Ville2:44 PMLyon Part Dieu$871One-way1 transfer
6704+
1777312:05 PM4h39Mulhouse-Ville4:44 PMLyon Part Dieu$871One-way1 transfer
121799:56 AM3h03Mulhouse-Ville12:59 PMLyon Part Dieu$1101One-way0 transfers
FlixBus10:40 AM6h20Mulhouse, Gare Centrale5:00 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$381One-way0 transfers
FlixBus6:45 AM5h55Mulhouse, Gare Centrale12:40 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$431One-way0 transfers
FlixBus3:05 AM5h10Mulhouse, Gare Centrale8:15 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$431One-way0 transfers
KL1944+
KL143310:15 AM7h20EuroAirport Basel Mulhouse Freiburg5:35 PMLyon Saint Exupery Airport$12961One-way1 transfer
KL1948+
KL14356:30 PM4h20EuroAirport Basel Mulhouse Freiburg10:50 PMLyon Saint Exupery Airport$12961One-way1 transfer
KL1942+
KL14336:30 AM11h05EuroAirport Basel Mulhouse Freiburg5:35 PMLyon Saint Exupery Airport$12961One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Mulhouse to Lyon
Travel to Lyon easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Mulhouse to Lyon.

This is compared to other travel options from Mulhouse to Lyon:
A bus is $33 (€27) less than a train for this route with tickets for a train from Mulhouse to Lyon costing on average $49 (€40).
A bus is $92 (€75) less than a flight for this route with tickets for a flight from Mulhouse to Lyon costing on average $108 (€88).
Other travel options to Lyon take longer:
Bus takes on average 4h 25m.
Flight takes on average 3h 20m.
- Around 9 trains per day.
- Around 9 buses per day.
- Around 8 flights per day.
However, we recommend checking specific travel dates for your route between Mulhouse and Lyon as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from EuroAirport Basel Mulhouse Freiburg and arrive in Lyon Saint Exupery Airport.
- Trains mostly depart from Mulhouse-Ville and arrive in Lyon Part Dieu.
- Buses mostly depart from Mulhouse, Gare Centrale and arrive in Lyon, Perrache Bus Station.
- Travel with FlixBus, BlaBlaCar Bus, BlaBlaCar to go to Lyon by bus.
- Travel with TGV INOUI, SNCF TER | Operated by SNCF Voyageurs 1187, TER, Deutsche Bahn, Luxembourg Railways (CFL) to go to Lyon by train.
- 8 direct buses per day with FlixBus, BlaBlaCar Bus, BlaBlaCar.
- 6 direct trains per day with TGV INOUI, Deutsche Bahn, Luxembourg Railways (CFL).
Travelling from Mulhouse to Lyon: related information
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