Travel Information
Compare train, bus, and flight for Nantes to Lyon
Omio recommends booking the train as it is the most popular option from Nantes to Lyon among Omio's users. If you are prioritising price take the bus with prices starting from $30. For those with little time consider booking a flight which can get you there in 1h 19m. The ticket price range depends on the travel mode: a bus costs an average of $30, and a flight costs an average of $59.
Distance: 320 miles (516 km)
Compare train with
Most popular Train | Flight | Bus |
|---|---|---|
$96 Average price | $126 Average price | $51 Average price Cheapest |
5h 32m Average total duration 5h 2m Onboard + 30m Additional time* | 4h 19m Average total duration Fastest 1h 19m Onboard + 3h 0m Additional time* | 9h 47m Average total duration 9h 17m Onboard + 30m Additional time* |
![]() Most popular train company | ![]() Most popular airline | ![]() Most popular bus company |
Direct Options | Direct Options | Direct Options |
Travel optionsfrom Nantes to Lyon
How to get from Nantes to Lyon by train, bus or flight.
Our recommendation
The best way to travel from Nantes to Lyon is by taking a flight because it’s the best combination of price and speed.
V728183:25 PM1h10Nantes Atlantique Airport4:35 PMLyon Saint Exupery Airport$931One-way0 transfers
Cheapest
87086 · 51335:00 PM12h20Nantes, Route de Paris5:20 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$571One-way1 transfer
Fastest
V728183:25 PM1h10Nantes Atlantique Airport4:35 PMLyon Saint Exupery Airport$931One-way0 transfers
Other options
5482 · 125268:08 AM5h52Nantes station2:00 PMLyon Part Dieu$1481One-way1 transfer
530612:44 PM4h46Nantes station5:30 PMLyon Part Dieu$1531One-way0 transfers
8864 · 66138:04 AM5h52Nantes station1:56 PMLyon Part Dieu$1771One-way1 transfer
FlixBus8:35 PM10h15Nantes6:50 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$611One-way0 transfers
50025 · 31689:45 AM12h20Nantes, Route de Paris10:05 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$691One-way1 transfer
FlixBus · FlixBus10:45 AM13h05Nantes11:50 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$771One-way1 transfer
U243289:00 AM1h15Nantes Atlantique Airport10:15 AMLyon Saint Exupery Airport$1111One-way0 transfers
U243309:55 PM1h10Nantes Atlantique Airport11:05 PMLyon Saint Exupery Airport$1111One-way0 transfers
AF7505 · AF73682:20 PM3h50Nantes Atlantique Airport6:10 PMLyon Saint Exupery Airport$1511One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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FAQs: Travel from Nantes to Lyon
Travel to Lyon easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Nantes to Lyon.

This is compared to other travel options from Nantes to Lyon:
A bus is $2 (€2) less than a train for this route with tickets for a train from Nantes to Lyon costing on average $32 (€26).
A bus is $30 (€24) less than a flight for this route with tickets for a flight from Nantes to Lyon costing on average $59 (€48).
Other travel options to Lyon take longer:
Train takes on average 4h 26m.
Bus takes on average 9h 10m.
- Around 11 trains per day.
- Around 10 flights per day.
- Around 10 buses per day.
However, we recommend checking specific travel dates for your route between Nantes and Lyon as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Nantes Atlantique Airport and arrive in Lyon Saint Exupery Airport.
- Trains mostly depart from Nantes station and arrive in Lyon Part Dieu.
- Buses mostly depart from Nantes, Route de Paris and arrive in Lyon, Perrache Bus Station.
- Travel with FlixBus, BlaBlaCar Bus, BlaBlaCar to go to Lyon by bus.
- Travel with easyJet, Volotea, Air France to go to Lyon by flight.
- Travel with SNCF | Intercités, TGV INOUI, TGV, SNCF to go to Lyon by train.
- 4 direct buses per day with FlixBus, BlaBlaCar Bus, BlaBlaCar.
- 2 direct flights per day with easyJet, Air France.
- 4 direct trains per day with SNCF | Intercités, TGV INOUI, SNCF.
Travelling from Nantes to Lyon: related information
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