Travel Information
Compare train, bus, and flight for Pisa to Prague
Omio recommends booking the flight as it is the most popular option from Pisa to Prague among Omio's users. If you are prioritising price take the bus with prices starting from $61. For those with little time consider booking a flight which can get you there in 2h 26m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.8 - 1.9kg. The ticket price range depends on the travel mode: a bus costs an average of $61, and a train costs an average of $225.
Distance: 479 miles (771 km)
Compare flight with
Most popular Flight | Bus | Train |
|---|---|---|
$125 Average price | $99 Average price Cheapest | $258 Average price |
5h 26m Average total duration Fastest 2h 26m Onboard + 3h 0m Additional time* | 17h 16m Average total duration 16h 46m Onboard + 30m Additional time* | 20h 44m Average total duration 20h 14m Onboard + 30m Additional time* |
2.3 - 4.6kg CO2 emissions | 0.8 - 1.9kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular airline | ![]() Most popular bus company | |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Travel optionsfrom Pisa to Prague
How to get from Pisa to Prague by train, bus or flight.
Our recommendation
The best way to travel from Pisa to Prague is by taking a bus because it’s the best combination of price and speed.
FlixBus5:10 PM16h15Pisa, Via delle Fiamme Gialle (Park Pietrasantina)9:25 AMPraha, ÚAN Florenc$1911One-way0 transfers
Cheapest
FlixBus · FlixBus · FlixBus7:15 AM22h30Pisa, Via delle Fiamme Gialle (Park Pietrasantina)5:45 AMPraha, ÚAN Florenc$1741One-way2 transfers
Fastest
ETRUSCHI LINE 4125 · Regionale 20445+
QS10095:45 AM10h15Pisa Centrale4:00 PMPrague Vaclav Havel Airport$6161One-way2 transfers
Other options
FlixBus · FlixBus · FlixBus5:10 PM18h35Pisa, Via delle Fiamme Gialle (Park Pietrasantina)11:45 AMPraha, Na Knížecí$2021One-way2 transfers
FlixBus · FlixBus · FlixBus5:10 PM23h00Pisa, Via delle Fiamme Gialle (Park Pietrasantina)4:10 PMPraha, Černý Most$1881One-way2 transfers
FlixBus · FlixBus5:10 PM17h25Pisa, Via delle Fiamme Gialle (Park Pietrasantina)10:35 AMPrague, Central Train Station$2261One-way1 transfer
InterCityNotte 799+
Regionale 20399+
LO302 · LO5212:34 AM14h51Pisa Centrale5:25 PMPrague Vaclav Havel Airport$3251One-way3 transfers
ETRUSCHI LINE 4127 · Regionale 20459+
LO304 · LO5237:45 AM25h30Pisa Centrale9:15 AMPrague Vaclav Havel Airport$3121One-way3 transfers
ETRUSCHI LINE 4127 · Regionale 20459+
LO304 · LO5277:45 AM28h20Pisa Centrale12:05 PMPrague Vaclav Havel Airport$3121One-way3 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Pisa to Prague
Travel to Prague easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Pisa to Prague.

This is compared to other travel options from Pisa to Prague:
A flight is $36 (€29) less than a bus for this route with tickets for a bus from Pisa to Prague costing on average $61 (€49).
A flight is $200 (€163) less than a train for this route with tickets for a train from Pisa to Prague costing on average $225 (€183).
Other travel options to Prague take longer:
Bus takes on average 16h 5m.
Train takes on average 14h 55m.
- Around 12 buses per day.
- Around 7 flights per day.
- Around 5 trains per day.
However, we recommend checking specific travel dates for your route between Pisa and Prague as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Pisa International Airport and arrive in Prague Vaclav Havel Airport.
- Buses mostly depart from Pisa, Via delle Fiamme Gialle (Park Pietrasantina) and arrive in Prague, Central Train Station.
- Travel with Regionale to go to Prague by train.
- Travel with Malta Air, Buzz, Ryanair, Norwegian Air, Air Dolomiti to go to Prague by flight.
- Travel with FlixBus to go to Prague by bus.
- 1 direct flights per day with Malta Air, Buzz.
- 1 direct buses per day with FlixBus.
Travelling from Pisa to Prague: related information
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