Travel Information
Compare train, bus, and flight for Pisa to Brussels
Omio recommends booking the flight as it is the most popular option from Pisa to Brussels among Omio's users. If you are prioritising price take the bus with prices starting from $74. For those with little time consider booking a flight which can get you there in 2h 30m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.9 - 2.3kg. The ticket price range depends on the travel mode: a bus costs an average of $74, and a train costs an average of $362.
Distance: 567 miles (914 km)
Compare flight with
Most popular Flight | Bus | Train |
|---|---|---|
$126 Average price | $124 Average price Cheapest | $362 Average price |
5h 30m Average total duration Fastest 2h 30m Onboard + 3h 0m Additional time* | 21h 28m Average total duration 20h 58m Onboard + 30m Additional time* | 21h 8m Average total duration 20h 38m Onboard + 30m Additional time* |
2.7 - 5.5kg CO2 emissions | 0.9 - 2.3kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular airline | ![]() Most popular bus company | |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Travel optionsfrom Pisa to Brussels
How to get from Pisa to Brussels by train, bus or flight.
Our recommendation
The best way to travel from Pisa to Brussels is by taking a flight because it’s the best combination of price and speed.
FR 374611:35 AM1h45Pisa International Airport1:20 PMBrussels South Charleroi Airport$1271One-way0 transfers
Cheapest
FR 37477:45 PM1h45Pisa International Airport9:30 PMBrussels South Charleroi Airport$1241One-way0 transfers
Fastest
FR 374611:35 AM1h45Pisa International Airport1:20 PMBrussels South Charleroi Airport$1271One-way0 transfers
Other options
FlixBus · FlixBus · FlixBus1:50 PM28h05Pisa, Via delle Fiamme Gialle (Park Pietrasantina)5:55 PMBrussels, Brussels South (Gare du Midi)$2311One-way2 transfers
FlixBus · FlixBus · FlixBus6:25 AM25h50Pisa, Via delle Fiamme Gialle (Park Pietrasantina)8:15 AMBrussels, Brussels South (Gare du Midi)$2481One-way2 transfers
HV5424+
93983:25 PM7h41Pisa International Airport11:06 PMBrussels-Midi$3981One-way1 transfer
HV5424+
93943:25 PM6h41Pisa International Airport10:06 PMBrussels-Midi$4181One-way1 transfer
HV5424+
93883:25 PM5h41Pisa International Airport9:06 PMBrussels-Midi$4691One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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FAQs: Travel from Pisa to Brussels
Travel to Brussels easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Pisa to Brussels.

This is compared to other travel options from Pisa to Brussels:
A flight is $53 (€43) less than a bus for this route with tickets for a bus from Pisa to Brussels costing on average $74 (€60).
A flight is $341 (€278) less than a train for this route with tickets for a train from Pisa to Brussels costing on average $362 (€295).
Other travel options to Brussels take longer:
Train takes on average 20h 38m.
Bus takes on average 22h 35m.
- Around 5 flights per day.
- Around 5 buses per day.
- Around 1 trains per day.
However, we recommend checking specific travel dates for your route between Pisa and Brussels as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Pisa International Airport and arrive in Brussels Airport.
- Buses mostly depart from Pisa, Via delle Fiamme Gialle (Park Pietrasantina) and arrive in Brussels, Brussels South (Gare du Midi).
- Travel with Regionale to go to Brussels by train.
- Travel with Ryanair, Malta Air, Vueling, Air Dolomiti to go to Brussels by flight.
- Travel with FlixBus to go to Brussels by bus.
- 2 direct flights per day with Malta Air.
Travelling from Pisa to Brussels: related information
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