Travel Information
Compare train and bus for Brussels to Karlsruhe
Omio recommends booking the train as it is the most popular option from Brussels to Karlsruhe among Omio's users. If you are prioritising price take the bus with prices starting from $24. For those with little time consider booking a train which can get you there in 4h 20m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.3kg. The ticket price range depends on the travel mode: a bus costs an average of $24, and a train costs an average of $39.
Distance: 219 miles (354 km)
Compare train with
Most popular Train | Bus |
|---|---|
$143 Average price | $52 Average price Cheapest |
4h 50m Average total duration Fastest 4h 20m Onboard + 30m Additional time* | 8h 56m Average total duration 8h 26m Onboard + 30m Additional time* |
0.1 - 0.3kg CO2 emissions Lowest | 0.4 - 0.9kg CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Travel optionsfrom Brussels to Karlsruhe
How to get from Brussels to Karlsruhe by train, bus or flight.
Our recommendation
The best way to travel from Brussels to Karlsruhe is by taking a bus because it’s the best combination of price and speed.
50345 · 304925:35 PM9h30Brussels, Brussels South (Gare du Midi)3:05 AMKarlsruhe, Hinterm Hauptbahnhof (Südeingang)$561One-way1 transfer
Cheapest
50345 · 304925:35 PM9h30Brussels, Brussels South (Gare du Midi)3:05 AMKarlsruhe, Hinterm Hauptbahnhof (Südeingang)$561One-way1 transfer
Fastest
SN2617+
ICE 2057:30 PM3h29Brussels Airport10:59 PMKarlsruhe Hbf$6351One-way1 transfer
Other options
ICE 13 · ICE 1058:25 AM4h34Brussels-Midi12:59 PMKarlsruhe Hbf$1971One-way1 transfer
ICE 15 · ICE 10710:25 AM4h34Brussels-Midi2:59 PMKarlsruhe Hbf$1971One-way1 transfer
ICE 15 · ICE 1644 · ICE 37310:25 AM5h34Brussels-Midi3:59 PMKarlsruhe Hbf$1971One-way2 transfers
FlixBus · FlixBus4:15 PM10h45Brussels, Brussels South (Gare du Midi)3:00 AMKarlsruhe Hbf$581One-way1 transfer
KL1706+
KL1821+
ICE 2053:10 PM7h49Brussels Airport10:59 PMKarlsruhe Hbf$4191One-way2 transfers
KL1704+
KL1819+
ICE 10910:25 AM6h34Brussels Airport4:59 PMKarlsruhe Hbf$4401One-way2 transfers
KL1706+
KL1821+
ICE 1015 · ECE 93:10 PM6h13Brussels Airport9:23 PMKarlsruhe Hbf$4301One-way3 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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FAQs: Travel from Brussels to Karlsruhe
Travel to Karlsruhe easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Brussels to Karlsruhe.

This is compared to other travel options from Brussels to Karlsruhe:
A bus is $15 (€12) less than a train for this route with tickets for a train from Brussels to Karlsruhe costing on average $39 (€31).
Other travel options to Karlsruhe take longer:
Bus takes on average 7h 15m.
- Around 6 trains per day.
- Around 3 buses per day.
However, we recommend checking specific travel dates for your route between Brussels and Karlsruhe as scheduled services by train and bus can vary by season or day of the week.
- Trains mostly depart from Brussels-Midi and arrive in Karlsruhe Hbf.
- Buses mostly depart from Brussels, Brussels South (Gare du Midi) and arrive in Karlsruhe Hbf.
- Travel with FlixBus, BlaBlaCar Bus, Union Ivkoni International to go to Karlsruhe by bus.
- Travel with Deutsche Bahn, Deutsche Bahn Intercity (DB IC) to go to Karlsruhe by train.
- 1 direct buses per day with FlixBus.
Travelling from Brussels to Karlsruhe: related information
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