Travel Information
Compare train and bus for Lyon to Karlsruhe
Omio recommends booking the train as it is the most popular option from Lyon to Karlsruhe among Omio's users. If you are prioritising price take the bus with prices starting from $25. For those with little time consider booking a train which can get you there in 4h 42m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a bus costs an average of $25, and a train costs an average of $64.
Distance: 278 miles (449 km)
Compare train with
Most popular Train | Bus |
|---|---|
$130 Average price | $43 Average price Cheapest |
5h 12m Average total duration Fastest 4h 42m Onboard + 30m Additional time* | 8h 22m Average total duration 7h 52m Onboard + 30m Additional time* |
0.1 - 0.4kg CO2 emissions Lowest | 0.4 - 1.1kg CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Travel optionsfrom Lyon to Karlsruhe
How to get from Lyon to Karlsruhe by train, bus or flight.
Our recommendation
The best way to travel from Lyon to Karlsruhe is by taking a bus because it’s the best combination of price and speed.
3415202:05AM8h45Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)10:50AMKarlsruhe, Hinterm Hauptbahnhof (Südeingang)$501One-way0 transfers
Cheapest
3415202:05AM8h45Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)10:50AMKarlsruhe, Hinterm Hauptbahnhof (Südeingang)$501One-way0 transfers
Fastest
LH1083+
ICE 10306:35AM4h24Lyon Saint Exupery Airport10:59AMKarlsruhe Hbf$4811One-way1 transfer
Other options
TGV 958310:01AM4h49Lyon Part Dieu02:50PMKarlsruhe Hbf$1431One-way0 transfers
9898+
957308:32AM4h52Lyon Part Dieu01:24PMKarlsruhe Hbf$1731One-way1 transfer
5516+
956311:38AM6h14Lyon Part Dieu05:52PMKarlsruhe Hbf$1601One-way1 transfer
FlixBus05:20AM7h55Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)01:15PMKarlsruhe Hbf$661One-way0 transfers
FlixBus07:30AM10h30Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)06:00PMKarlsruhe Hbf$731One-way0 transfers
FlixBus05:05PM8h45Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)01:50AMKarlsruhe Hbf$671One-way0 transfers
KL1428+
KL1819+
ICE 10909:55AM7h04Lyon Saint Exupery Airport04:59PMKarlsruhe Hbf$4591One-way2 transfers
EN8911+
ICE 10710:30AM4h29Lyon Saint Exupery Airport02:59PMKarlsruhe Hbf$4901One-way1 transfer
LH5673+
ICE 10710:30AM4h29Lyon Saint Exupery Airport02:59PMKarlsruhe Hbf$4901One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
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FAQs: Travel from Lyon to Karlsruhe
Travel to Karlsruhe easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Lyon to Karlsruhe.

This is compared to other travel options from Lyon to Karlsruhe:
A bus is $39 (€32) less than a train for this route with tickets for a train from Lyon to Karlsruhe costing on average $64 (€51).
Other travel options to Karlsruhe take longer:
Bus takes on average 7h 55m.
- Around 8 buses per day.
- Around 6 trains per day.
However, we recommend checking specific travel dates for your route between Lyon and Karlsruhe as scheduled services by train and bus can vary by season or day of the week.
- Trains mostly depart from Lyon Part Dieu and arrive in Karlsruhe Hbf.
- Buses mostly depart from Lyon, Perrache Bus Station and arrive in Karlsruhe Hbf.
- Travel with FlixBus, BlaBlaCar Bus, BlaBlaCar to go to Karlsruhe by bus.
- Travel with TGV, TGV INOUI to go to Karlsruhe by train.
- 5 direct buses per day with FlixBus, BlaBlaCar Bus, BlaBlaCar.
- 2 direct trains per day with TGV, TGV INOUI.
Travelling from Lyon to Karlsruhe: related information
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