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Travel Information
Compare bus and flight for St. Louis, MO to Winston Salem, NC
Omio recommends booking the bus as it is the most popular option from St. Louis, MO to Winston Salem, NC among Omio's users. If you are prioritising price take the bus with prices starting from $217. For those with little time consider booking a flight which can get you there in 5h 43m. The ticket price range depends on the travel mode: a bus costs an average of $217, and a flight costs an average of $308.
Distance: 573 miles (923 km)
Compare bus with
Most popular Bus | Flight |
|---|---|
$227 Average price Cheapest | $308 Average price |
25h 18m Average total duration 24h 48m Onboard + 30m Additional time* | 8h 43m Average total duration Fastest 5h 43m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options |
Live departures
St. Louis, MO to Winston Salem, NC bus times
The table below shows live departures for St. Louis, MO to Winston Salem, NC buses for today, Friday, April 3. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
 | 8:45 AM St. Louis, MO | 25h30 | 10:15 AM Winston Salem, NC | 3 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets St. Louis, MO to Winston Salem, NC by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book St. Louis, MO to Winston Salem, NC buses with Omio?
Greyhound operates all buses services from St. Louis, MO to Winston Salem, NC.
Omio is an official ticket reseller for all your travel options from St. Louis, MO to Winston Salem, NC.
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus and flight to ensure you get the best deal for traveling from St. Louis, MO to Winston Salem, NC.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from St. Louis, MO to Winston Salem, NC.
Journey information
Overview: Bus from St. Louis, MO to Winston Salem, NC
USAUSA
Buses from St. Louis, MO to Winston Salem, NC run on average 3 times per day, taking around 24h 48m. Cheap bus tickets for this journey start at $217 (€177) if you book in advance.
The earliest bus runs at 08:30, the last at 23:30. The fastest bus covers the 573 miles (923 km) distance in 19h 20m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 573 miles (923 km) |
Average bus duration 24h 48m |
Cheapest ticket price $217 (€177) |
Buses per day 3 |
Fastest bus 19h 20m |
First bus 8:30 AM |
Last bus 11:30 PM |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: Greyhound from St. Louis, MO to Winston Salem, NCYou can travel by bus between St. Louis, MO to Winston Salem, NC with Greyhound for as low as $217 (€177). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
19h 20m
Cheapest Price
$217 (€177)
Greyhound frequency
2 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
FAQs: Bus from St. Louis, MO to Winston Salem, NC
Find answers to the most common questions about traveling from St. Louis, MO to Winston Salem, NC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Winston Salem, NC, this guide helps you travel smarter and with confidence.
Cheap bus tickets from St. Louis, MO to Winston Salem, NC can start from as little as $217 (€177) when you book in advance. The average bus ticket price for St. Louis, MO to Winston Salem, NC is $227 (€185) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from St. Louis, MO to Winston Salem, NC is 19h 20m to travel the 573 miles (923 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from St. Louis, MO to Winston Salem, NC leaves at 8:30 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from St. Louis, MO to Winston Salem, NC leaves at 11:30 PM.
There are 3 buses a day from St. Louis, MO to Winston Salem, NC which require at least one change with Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from St. Louis, MO to Winston Salem, NC, you can count on Greyhound for the best way to get you to Winston Salem, NC. You can also check all possible bus companies who offer a service between St. Louis, MO and Winston Salem, NC and compare the amenities they offer before buying a bus ticket.
A trip to Winston Salem, NC from St. Louis, MO is worth doing but not as a day trip with a journey time of 19h 20m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from St. Louis, MO to Winston Salem, NC is July.
It's helpful to compare your options as there are 2 ways to travel between St. Louis, MO and Winston Salem, NC including taking a bus and flight.
Yes, the following accessibility options are available when taking the bus from St. Louis, MO to Winston Salem, NC:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from St. Louis, MO to Winston Salem, NC for bus company Greyhound.
Whether you can cancel your bus ticket from St. Louis, MO to Winston Salem, NC depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from St. Louis, MO to Winston Salem, NC.
Yes, the following luggage options are included when booking a bus ticket from St. Louis, MO to Winston Salem, NC:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from St. Louis, MO to Winston Salem, NC:
- Greyhound
- $15 per additional bag.
Unfortunately, pets are not allowed on the bus from St. Louis, MO to Winston Salem, NC.
You can reserve your seat on the bus from St. Louis, MO to Winston Salem, NC with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from St. Louis, MO to Winston Salem, NC with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from St. Louis, MO to Winston Salem, NC with the following bus company: Greyhound.
Since neither St. Louis, MO nor Winston Salem, NC are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the bus as it is the most popular way to get from St. Louis, MO to Winston Salem, NC among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Winston Salem, NC, travelers should be cautious of petty theft and pickpocketing, especially in crowded areas and downtown nightlife spots. Scams involving overcharging by unofficial taxi services can occur, so it’s recommended to use licensed transportation options. Additionally, travelers should stay aware of their surroundings in less populated areas after dark and avoid displaying valuables openly to reduce safety risks.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from St. Louis, MO to Winston Salem, NC
St. Louis
Winston Salem
The major bus station for departures in St. Louis is St. Louis, S 15th St (Civic center). Find all the information you need to know about services, amenities and connections at St. Louis, S 15th St (Civic center) for your trip from St. Louis to Winston Salem.
St. Louis, S 15th St (Civic center)
information
The major bus station for arrivals in Winston Salem is Winston Salem, W 5th St (Greyhound Bus Station). Find all the information you need to know about services, amenities and connections at Winston Salem, W 5th St (Greyhound Bus Station) for your trip to Winston Salem from St. Louis.
Winston Salem, W 5th St (Greyhound Bus Station)
information
Most popular bus connections from St. Louis, MO
More options for your journey from St. Louis, MO to Winston Salem, NC
Here are some other resources that might have the information you need
Most popular buses to and from Winston Salem, NC and St. Louis, MO
Most popular bus connections to Winston Salem, NC
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